Benzyl 4-oxo-1,4'-bipiperidine-1'-carboxylate

Base Information

Chemical Name:Benzyl 4-oxo-1,4'-bipiperidine-1'-carboxylate
CAS No.:880462-12-4
Molecular Formula:C18H24N2O3
Molecular Weight:316.4
Hs Code.:
DSSTox Substance ID:DTXSID10701293
Wikidata:Q82632896
Mol file:880462-12-4.mol

Synonyms:880462-12-4;benzyl 4-oxo-1,4'-bipiperidine-1'-carboxylate;SCHEMBL1930828;DTXSID10701293;NXKIYKXWPWOYAD-UHFFFAOYSA-N;MFCD09953018;D84432;Benzyl 4-oxo[1,4'-bipiperidine]-1'-carboxylate;BENZYL 4-OXO-[1,4'-BIPIPERIDINE]-1'-CARBOXYLATE;BENZYL 4-(4-OXOPIPERIDIN-1-YL)PIPERIDINE-1-CARBOXYLATE

Suppliers and Price of Benzyl 4-oxo-1,4'-bipiperidine-1'-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
BENZYL-4-(4-OXOPIPERIDIN-1-YL)PIPERIDINE-1-CARBOXYLATE 95.00%
5MG
$ 499.75

Total 2 raw suppliers

Chemical Property of Benzyl 4-oxo-1,4'-bipiperidine-1'-carboxylate

Chemical Property:

PSA：49.85000
LogP:2.32830
XLogP3:1.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:316.17869263
Heavy Atom Count:23
Complexity:403

Purity/Quality:

99% ，98% ^*data from raw suppliers

BENZYL-4-(4-OXOPIPERIDIN-1-YL)PIPERIDINE-1-CARBOXYLATE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CCC1N2CCC(=O)CC2)C(=O)OCC3=CC=CC=C3

Technology Process of Benzyl 4-oxo-1,4'-bipiperidine-1'-carboxylate

There total 5 articles about Benzyl 4-oxo-1,4'-bipiperidine-1'-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 880462-11-3
N-[(benzyloxy)carbonyl]-4-(1,4-dioxa-8-aza-spiro[4.5]dec-8-yl)-piperidine

: 880462-12-4
N-[(benzyloxy)carbonyl]-4-oxo-[1,4']bipiperidine

Guidance literature:: With hydrogenchloride; at 0 - 20 ℃;
DOI:10.1002/anie.200502991

Reference yield:

: 19099-93-5
benzyl 4-oxo-1-piperidinecarboxylate

: 880462-12-4
N-[(benzyloxy)carbonyl]-4-oxo-[1,4']bipiperidine

Guidance literature:: Multi-step reaction with 2 steps

1: 56 percent / NaBH(OAc)3 / 1,2-dichloro-ethane / 20 °C

2: 72 percent / aq. HCl / 0 - 20 °C

With hydrogenchloride; sodium tris(acetoxy)borohydride; In 1,2-dichloro-ethane;
DOI:10.1002/anie.200502991