1-Cbz-4-Piperidone

Base Information Edit

Chemical Name:1-Cbz-4-Piperidone
CAS No.:19099-93-5
Molecular Formula:C13H15NO3
Molecular Weight:233.267
Hs Code.:29333990
European Community (EC) Number:606-227-7
DSSTox Substance ID:DTXSID50349198
Nikkaji Number:J305.987A
Wikidata:Q72516433
Mol file:19099-93-5.mol

Synonyms:19099-93-5;1-Cbz-4-Piperidone;benzyl 4-oxopiperidine-1-carboxylate;N-Benzyloxycarbonyl-4-piperidone;1-Cbz-piperidin-4-one;1-(Benzyloxycarbonyl)-4-piperidinone;Benzyl 4-oxo-1-piperidinecarboxylate;n-(benzyloxycarbonyl)-4-piperidone;N-CBZ-4-piperidone;1-piperidinecarboxylic acid, 4-oxo-, phenylmethyl ester;MFCD00673144;1-BENZYLOXYCARBONYL-4-PIPERIDONE;4-Oxo-1-piperidinecarboxylic Acid Benzyl Ester;1-Z-4-Piperidone;N-Cbz-4-piperidinone;N-Cbz-piperid-4-one;4-oxo-N-CBZ-piperidine;N-CBZ-piperidine-4-one;N-Carbobenzoxy-4-piperidone;1-Carbobenzoxy-4-piperidone;SCHEMBL61861;1-Carbobenzyloxy-4-piperidone;1-Z-4-Piperidone, 99%;1-Benzyloxycarbonyl-4-piperidine;N-(carbobenzyloxy)-4-piperidone;DTXSID50349198;N-benzyloxy carbonyl-4-piperidone;n-benzyloxycarbonylpiperidin-4-one;1-benzyloxycarbonyl piperidin4-one;1-Benzyloxycarbonyl-4 -piperidone;1-benzyloxycarbonylpiperidin-4-one;N-benzyloxycarbonyl-4-piperidinone;N-benzyloxycarbonyl-4-oxopiperidine;1-(Benzyloxycarbonyl)-4-piperidone;1-benzyloxycarbonyl piperidin-4-one;1-benzyloxycarbonyl-4-oxopiperidine;benzyl 4-oxopiperidin-1-carboxylate;N-benzyloxycarbonyl-piperidin-4-one;STR04300;1-phenylmethoxycarbonyl-4-piperidone;benzyl-4-oxo-1-piperidinecarboxylate;benzyl-4-oxopiperidine-1-carboxylate;N-CARBOBENZYLOXY-4-PIPERIDONE;1-(Benzyloxycarbonyl)piperidine-4-one;AKOS005259566;benzyl 4-oxo- 1-piperidinecarboxylate;benzyl 4-oxo-1-piperidine carboxylate;benzyl 4-oxo-1-piperidine-carboxylate;benzyl 4-oxo-piperidine-1-carboxylate;Benzyl-4-oxo-1-piperidine carboxylate;Benzyl(4-oxopiperidin-1-yl)carboxylate;CS-W002665;PB33913;PS-5181;Benzyl (4-oxopiperidin-1-yl)carboxylate;AC-22468;PIPERIDIN-4-ONE, N-CBZ PROTECTED;SY008055;phenylmethyl 4-oxo-1-piperidinecarboxylate;1-(BENZYLOXYCARBONYL)PIPERIDIN-4-ONE;A4214;AM20060364;B3643;FT-0630091;EN300-69990;1-Z-4-Piperidone, purum, >=95.0% (HPLC);Q-102992;4-OXO-PIPERIDINE-1-CARBOXYLIC ACID BENZYL ESTER;1-(Benzyloxycarbonyl)-4-piperidinone, 1-Cbz-4-Piperidone, Benzyl 4-oxo-1-piperidinecarboxylate

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Chemical Property of 1-Cbz-4-Piperidone Edit

Chemical Property:

Appearance/Colour:colourless oil
Vapor Pressure:4.18E-06mmHg at 25°C
Melting Point:38-41 °C
Refractive Index:n20/D 1.542(lit.)
Boiling Point:384.1 °C at 760 mmHg
PKA:-1.63±0.20(Predicted)
Flash Point:186.1 °C
PSA：46.61000
Density:1.212 g/cm³
LogP:1.92600
Storage Temp.:Refrigerator
Solubility.:Chloroform, Dichloromethane, Ethyl Acetate, Methanol
XLogP3:1.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:233.10519334
Heavy Atom Count:17
Complexity:274

Purity/Quality:

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 23-24/25-36-26-37/39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CCC1=O)C(=O)OCC2=CC=CC=C2
Uses Protected piperidinone that can undergo interesting synthetic transformations including the Knoevenagel reaction,1 hetero-Diels-Alder reactions,2 and reactions to form N-(4-piperidinyl)oxindoles.3

Technology Process of 1-Cbz-4-Piperidone

There total 33 articles about 1-Cbz-4-Piperidone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%