2-Palmitoylglycerol

Base Information

Chemical Name:2-Palmitoylglycerol
CAS No.:23470-00-0
Molecular Formula:C19H38 O4
Molecular Weight:330.508
Hs Code.:2915709000
UNII:21I29V2935
DSSTox Substance ID:DTXSID30178024
Nikkaji Number:J103.626B
Wikidata:Q27145323
Metabolomics Workbench ID:5775
ChEMBL ID:CHEMBL1317070
Mol file:23470-00-0.mol

Synonyms:2-Palm-Gl;2-palmitoyl-glycerol;2-palmitoylglycerol

Suppliers and Price of 2-Palmitoylglycerol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
2-Palmitoyl-rac-glycerol
25mg
$ 460.00

TRC
2-Palmitoyl-rac-glycerol
250mg
$ 1100.00

TRC
2-Palmitoyl-rac-glycerol
10mg
$ 70.00

Sigma-Aldrich
2-Palmitoylglycerol analytical standard
25mg
$ 335.00

Crysdot
1,3-Dihydroxypropan-2-ylpalmitate 95+%
10mg
$ 125.00

Cayman Chemical
2-Palmitoyl Glycerol ≥95%
25mg
$ 131.00

Cayman Chemical
2-Palmitoyl Glycerol ≥95%
50mg
$ 245.00

Cayman Chemical
2-Palmitoyl Glycerol ≥95%
10mg
$ 56.00

Cayman Chemical
2-Palmitoyl Glycerol ≥95%
5mg
$ 35.00

ApexBio Technology
2-Palmitoylglycerol
10mg
$ 125.00

Total 24 raw suppliers

Chemical Property of 2-Palmitoylglycerol

Chemical Property:

Melting Point:68-70°C
Refractive Index:1.4434 (estimate)
Boiling Point:460.6°Cat760mmHg
PKA:13.54±0.10(Predicted)
Flash Point:150.8°C
PSA：66.76000
Density:0.969g/cm³
LogP:4.36410
Storage Temp.:−20°C
Solubility.:Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
XLogP3:6.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:18
Exact Mass:330.27700969
Heavy Atom Count:23
Complexity:252

Purity/Quality:

98%Min ^*data from raw suppliers

2-Palmitoyl-rac-glycerol ^*data from reagent suppliers

Safty Information:

Pictogram(s): 1796692
Hazard Codes:Xi
Statements: 43
Safety Statements: 36/37

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCCCCCCCCCCCCCC(=O)OC(CO)CO
Description 2-Arachidonoyl glycerol (2-AG; ) is an endogenous agonist of the CB1 and CB2 cannabinoid receptors. 2-Palmitoyl glycerol is a fatty acid ester that does not bind directly to cannabinoid receptors, nor inhibit adenylyl cyclase, but rather potentiates the activity of 2-AG (and other endocannabinoids) to bind to CB1 and CB2 and inhibit adenylyl cyclase. This “entourage” effect has been attributed to blockade of the breakdown and reuptake pathways that normally function to reduce endocannabinoid levels rapidly upon release. 2-Palmitoyl glycerol and related endogenous fatty acid derivatives have been shown to interact with endocannabinoids in the modulation of pain sensitivity.
Uses A biomarker of metabolic responses to hepatotoxicants and carcinogens.

Technology Process of 2-Palmitoylglycerol

There total 14 articles about 2-Palmitoylglycerol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 56599-87-2
2-O-palmitoyl-1,3-O-benzylideneglycerol

: 23470-00-0
2-palmitoylglycerol

Guidance literature:: With hydrogen; palladium on activated charcoal; In ethyl acetate; at 20 ℃; for 72h;
DOI:10.1016/S0040-4020(03)00282-5

Reference yield: 84.4%

: 555-44-2
glyceroltripalmitate

: 23470-00-0
2-palmitoylglycerol

Guidance literature:: With Lipozyme TL-IM lipase; In ethanol; tert-butyl methyl ether; at 20 ℃; for 0.25h;

Reference yield: 80.0%

: 101036-66-2
1,3-dibutyryl-2-palmitoylglycerol

: 23470-00-0
2-palmitoylglycerol

Guidance literature:: With Rhizomucor miehei lipase; ethanol; at 20 ℃; for 24h; regiospecific reaction; Enzymatic reaction;
DOI:10.1016/j.tet.2012.04.101