1H-Indole-1-carboxylic acid, 3-[[[[3,5-bis(trifluoromethyl)phenyl]methyl]amino]methyl]-2-cyclopropyl-2, 3-dihydro-5-(trifluoromethyl)-, ethyl ester

Base Information

Chemical Name:1H-Indole-1-carboxylic acid, 3-[[[[3,5-bis(trifluoromethyl)phenyl]methyl]amino]methyl]-2-cyclopropyl-2, 3-dihydro-5-(trifluoromethyl)-, ethyl ester
CAS No.:880558-87-2
Molecular Formula:C25H23F9N2O2
Molecular Weight:554.455
Hs Code.:

1H-Indole-1-carboxylic acid,
3-[[[[3,5-bis(trifluoromethyl)phenyl]methyl]amino]methyl]-2-cyclopropyl-2,
3-dihydro-5-(trifluoromethyl)-, ethyl ester

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Chemical Property of 1H-Indole-1-carboxylic acid, 3-[[[[3,5-bis(trifluoromethyl)phenyl]methyl]amino]methyl]-2-cyclopropyl-2, 3-dihydro-5-(trifluoromethyl)-, ethyl ester

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Technology Process of 1H-Indole-1-carboxylic acid, 3-[[[[3,5-bis(trifluoromethyl)phenyl]methyl]amino]methyl]-2-cyclopropyl-2, 3-dihydro-5-(trifluoromethyl)-, ethyl ester

There total 1 articles about 1H-Indole-1-carboxylic acid, 3-[[[[3,5-bis(trifluoromethyl)phenyl]methyl]amino]methyl]-2-cyclopropyl-2, 3-dihydro-5-(trifluoromethyl)-, ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

: 880558-84-9
ethyl 2-cyclopropyl-5-(trifluoromethyl)-3-formylindoline-1-carboxylate

: 85068-29-7
3,5-bis-trifluoromethylbenzylamine

: 880558-87-2
ethyl 3-((3,5-bis(trifluoromethyl)benzylamino)methyl)-2-cyclopropyl-5-(trifluoromethyl)indoline-1-carboxylate

Guidance literature:: ethyl 2-cyclopropyl-5-(trifluoromethyl)-3-formylindoline-1-carboxylate; 3,5-bis-trifluoromethylbenzylamine; With sodium cyanoborohydride; acetic acid; In tetrahydrofuran;

With sodium hydrogencarbonate; In water; ethyl acetate; Saturated solution;