N-NITROSO-4-METHYLAMINOBENZALDEHYDE

Base Information

• Chemical Name: N-NITROSO-4-METHYLAMINOBENZALDEHYDE
• CAS No.: 7431-19-8
• Molecular Formula: C8H8N2O2
• Molecular Weight: 164.164
• Mol file: 7431-19-8.mol

Synonyms:

Chemical Property of N-NITROSO-4-METHYLAMINOBENZALDEHYDE

Chemical Property:

• Vapor Pressure: 0.000197mmHg at 25°C
• Boiling Point: 327.8°Cat760mmHg
• Flash Point: 152.1°C
• PSA: 58.53000
• Density: 1.2g/cm³
• LogP: 1.70790

Purity/Quality:

N-NITROSO-4-METHYLAMINOBENZALDEHYDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-NITROSO-4-METHYLAMINOBENZALDEHYDE

There total 7 articles about N-NITROSO-4-METHYLAMINOBENZALDEHYDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

4-dimethylamino-benzaldehyde (100-10-7) → N-(4-formylphenyl)-N-methylnitrous amide (7431-19-8)

Guidance literature:

With tert.-butylnitrite; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; In acetonitrile; at 20 ℃; for 2h;

DOI:10.1039/c7gc02775c

Reference yield: 16.0%

4-dimethylamino-benzaldehyde (100-10-7) → 4-dimethylamino-3-nitrobenzaldehyde (59935-39-6) + N,N-Dimethyl-4-nitroaniline (100-23-2) + N-(4-formylphenyl)-N-methylnitrous amide (7431-19-8)

Guidance literature:

With acetic acid; sodium nitrite; for 96h; Product distribution; examination of further 4-substituted N,N-dimethylanilines;

DOI:10.1039/P29840000165

Reference yield:

hydrogenchloride (7647-01-0,15364-23-5) + 4,4'-bis(dimethylamino)benzhydrol (119-58-4) → p-dimethylaminonitrosobenzene (138-89-6) + N,N-Dimethyl-4-nitroaniline (100-23-2) + N-(4-formylphenyl)-N-methylnitrous amide (7431-19-8) + N-methyl-N-nitroso-4-nitroaniline (943-41-9)

Guidance literature:

at 0 ℃; Produkt 5:3-Nitro-4-dimethylamino-benzaldehyd;

upstream raw materials:

4-dimethylamino-benzaldehyde

4-(methylamino)benzaldehyde

hydrogenchloride

4,4'-bis(dimethylamino)benzhydrol

Downstream raw materials:

4-[4-(methyl-nitroso-amino)-benzylideneamino]-N-thiazol-2-yl-benzenesulfonamide

C₃₁H₂₆N₆O₂

C₃₁H₂₆N₆O₂

Refernces

• 1、 Jia, Xiaodong,Li, Pengfei,Shao, Yu,Yuan, Yu,Ji, Honghe,Hou, Wentao,Liu, Xiaofei,Zhang, Xuewen. "Highly selective sp3 C-N bond activation of tertiary anilines modulated by steric and thermodynamic factors". supporting information. p. 5568 - 5574. Retrieved 2017/12/06.