1H-Indole-1-carboxylic acid, 3-[2-(acetyloxy)ethyl]-2-[(1R)-2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-1-[[ (phenylmethoxy)carbonyl]amino]ethyl]-, 1,1-dimethylethyl ester

Base Information

Chemical Name:1H-Indole-1-carboxylic acid, 3-[2-(acetyloxy)ethyl]-2-[(1R)-2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-1-[[ (phenylmethoxy)carbonyl]amino]ethyl]-, 1,1-dimethylethyl ester
CAS No.:881027-53-8
Molecular Formula:C33H46N2O7Si
Molecular Weight:610.823
Hs Code.:

1H-Indole-1-carboxylic acid,
3-[2-(acetyloxy)ethyl]-2-[(1R)-2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-1-[[
(phenylmethoxy)carbonyl]amino]ethyl]-, 1,1-dimethylethyl ester

Synonyms:

Suppliers and Price of 1H-Indole-1-carboxylic acid, 3-[2-(acetyloxy)ethyl]-2-[(1R)-2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-1-[[ (phenylmethoxy)carbonyl]amino]ethyl]-, 1,1-dimethylethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1H-Indole-1-carboxylic acid, 3-[2-(acetyloxy)ethyl]-2-[(1R)-2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-1-[[ (phenylmethoxy)carbonyl]amino]ethyl]-, 1,1-dimethylethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1H-Indole-1-carboxylic acid, 3-[2-(acetyloxy)ethyl]-2-[(1R)-2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-1-[[ (phenylmethoxy)carbonyl]amino]ethyl]-, 1,1-dimethylethyl ester

There total 4 articles about 1H-Indole-1-carboxylic acid, 3-[2-(acetyloxy)ethyl]-2-[(1R)-2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-1-[[ (phenylmethoxy)carbonyl]amino]ethyl]-, 1,1-dimethylethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 881027-48-1
acetic acid 2-{2-[1-benzyloxycarbonylamino-2-(tert-butyl-dimethyl-silanyloxy)-ethyl]-1H-indol-3-yl}-ethyl ester

: 24424-99-5
di-tert-butyl dicarbonate

: 881027-53-8
3-(2-acetoxy-ethyl)-2-[1-benzyloxycarbonylamino-2-(tert-butyl-dimethyl-silanyloxy)-ethyl]-indole-1-carboxylic acid tert-butyl ester

Guidance literature:: With dmap; triethylamine; In dichloromethane; at 20 ℃;
DOI:10.3987/COM-05-S(K)11

Reference yield:

: {(S)-2-(tert-Butyl-dimethyl-silanyloxy)-1-[2-((Z)-3-hydroxy-propenyl)-phenylcarbamoyl]-ethyl}-carbamic acid benzyl ester

: 881027-53-8
3-(2-acetoxy-ethyl)-2-[1-benzyloxycarbonylamino-2-(tert-butyl-dimethyl-silanyloxy)-ethyl]-indole-1-carboxylic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: pyridine / 20 °C

2: Lawesson's reagent; pyridine / toluene / 0.17 h / Heating

3: 84 percent / (n-Bu)3SnH; Et₃B / tetrahydrofuran; toluene / 0.5 h / 20 °C

4: 81 percent / Et₃N; DMAP / CH₂Cl₂ / 20 °C

With Lawessons reagent; pyridine; dmap; triethyl borane; tri-n-butyl-tin hydride; triethylamine; In tetrahydrofuran; dichloromethane; toluene;
DOI:10.3987/COM-05-S(K)11

Reference yield:

: 881027-40-3
Acetic acid (Z)-3-{2-[(S)-2-benzyloxycarbonylamino-3-(tert-butyl-dimethyl-silanyloxy)-propionylamino]-phenyl}-allyl ester

: 881027-53-8
3-(2-acetoxy-ethyl)-2-[1-benzyloxycarbonylamino-2-(tert-butyl-dimethyl-silanyloxy)-ethyl]-indole-1-carboxylic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: Lawesson's reagent; pyridine / toluene / 0.17 h / Heating

2: 84 percent / (n-Bu)3SnH; Et₃B / tetrahydrofuran; toluene / 0.5 h / 20 °C

3: 81 percent / Et₃N; DMAP / CH₂Cl₂ / 20 °C

With Lawessons reagent; pyridine; dmap; triethyl borane; tri-n-butyl-tin hydride; triethylamine; In tetrahydrofuran; dichloromethane; toluene;
DOI:10.3987/COM-05-S(K)11