3-(beta-Hydroxy-gamma-(3-tolyloxy)propylamino)quinuclidine

Base Information

Chemical Name:3-(beta-Hydroxy-gamma-(3-tolyloxy)propylamino)quinuclidine
CAS No.:73823-51-5
Molecular Formula:C₁₇H₂₆N₂O₂
Molecular Weight:290.406
Hs Code.:
DSSTox Substance ID:DTXSID90994888
Nikkaji Number:J87.500G

Synonyms:BRN 5277579;2-Propanol, 1-(3-quinuclidinylamino)-3-(m-tolyloxy)-;3-(beta-Hydroxy-gamma-(3-tolyloxy)propylamino)quinuclidine;73823-51-5;DTXSID90994888;LS-122669;1-(3-Quinuclidinylamino)-3-(m-tolyloxy)-2-propanol;1-[(1-Azabicyclo[2.2.2]octan-3-yl)amino]-3-(3-methylphenoxy)propan-2-ol

Suppliers and Price of 3-(beta-Hydroxy-gamma-(3-tolyloxy)propylamino)quinuclidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 3-(beta-Hydroxy-gamma-(3-tolyloxy)propylamino)quinuclidine

Chemical Property:

Vapor Pressure:2.52E-09mmHg at 25°C
Boiling Point:461.8°Cat760mmHg
Flash Point:233.1°C
Density:1.15g/cm³
XLogP3:1.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:290.199428076
Heavy Atom Count:21
Complexity:318

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=CC=C1)OCC(CNC2CN3CCC2CC3)O

Technology Process of 3-(beta-Hydroxy-gamma-(3-tolyloxy)propylamino)quinuclidine

There total 4 articles about 3-(beta-Hydroxy-gamma-(3-tolyloxy)propylamino)quinuclidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

: 73823-48-0
3-<β-Hydroxy-γ-(3-tolyloxy)propylimino>quinuclidine

: 73823-51-5
3-<β-Hydroxy-γ-(3-tolyloxy)propylamino>quinuclidine

Guidance literature:: With sodium tetrahydroborate; In ethanol; for 20h; Ambient temperature;
DOI:10.1007/BF00765604

Reference yield:

: 3731-38-2
3-Quinuclidinone

: 73823-51-5
3-<β-Hydroxy-γ-(3-tolyloxy)propylamino>quinuclidine

Guidance literature:: Multi-step reaction with 2 steps

1: 81.5 percent / p-toluenesulfonic acid / toluene / 10 h / Heating

2: 63 percent / sodium borohydride / ethanol / 20 h / Ambient temperature

With sodium tetrahydroborate; toluene-4-sulfonic acid; In ethanol; toluene;
DOI:10.1007/BF00765604

Reference yield:

: 2186-25-6
m-tolyl glycidyl ether

: 73823-51-5
3-<β-Hydroxy-γ-(3-tolyloxy)propylamino>quinuclidine

Guidance literature:: Multi-step reaction with 3 steps

1: 88 percent / 23percent methanolic ammonia / 90 h / Ambient temperature

2: 81.5 percent / p-toluenesulfonic acid / toluene / 10 h / Heating

3: 63 percent / sodium borohydride / ethanol / 20 h / Ambient temperature

With sodium tetrahydroborate; ammonia; toluene-4-sulfonic acid; In ethanol; toluene;
DOI:10.1007/BF00765604