Ditazole

Base Information

• Chemical Name: Ditazole
• CAS No.: 18471-20-0
• Molecular Formula: C19H20 N2 O3
• Molecular Weight: 324.379
• Hs Code.: 2934999090
• European Community (EC) Number: 242-353-5
• UNII: H2BQI5Z8FT
• DSSTox Substance ID: DTXSID3022954
• Nikkaji Number: J10.995I
• Wikipedia: Ditazole
• Wikidata: Q754622
• NCI Thesaurus Code: C65442
• Metabolomics Workbench ID: 152068
• ChEMBL ID: CHEMBL2104306
• Mol file: 18471-20-0.mol

Synonyms:ditazol;ditazole;S 222;S-222

Chemical Property of Ditazole

Chemical Property:

• Vapor Pressure: 4.83E-11mmHg at 25°C
• Boiling Point: 505.5°Cat760mmHg
• Flash Point: 259.5°C
• PSA: 69.73000
• Density: 1.237g/cm³
• LogP: 2.79960
• Storage Temp.: Refrigerator
• Solubility.: Chloroform (Slightly), Methanol (Slightly)
• XLogP3: 2.7
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 7
• Exact Mass: 324.14739250
• Heavy Atom Count: 24
• Complexity: 351

Purity/Quality:

98%Min ^*data from raw suppliers

Ditazole ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C2=C(OC(=N2)N(CCO)CCO)C3=CC=CC=C3
• Uses: Ditazole is a weak anti-inflammatory drug and a novel inhibitor of platelet aggregation.
• Therapeutic Function: Antiinflammatory

Technology Process of Ditazole

There total 2 articles about Ditazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-Chlor-4,5-diphenyl-oxazol (49656-04-4) + 2,2'-iminobis[ethanol] (111-42-2) → Diethamphenazol (18471-20-0)

Guidance literature:

In ethanol; Heating;

DOI:10.1021/jm00311a051

Reference yield:

→ Diethamphenazol (18471-20-0)

Guidance literature:

upstream raw materials:

2-Chlor-4,5-diphenyl-oxazol

2,2'-iminobis[ethanol]

Refernces