CH 141

Base Information

• Chemical Name: CH 141
• CAS No.: 78279-88-6
• Molecular Formula: C19H21 N3 O
• Molecular Weight: 307.395
• Mol file: 78279-88-6.mol

Synonyms:2H-1,2,4-Oxadiazine,isoquinoline deriv.; CH 141

Chemical Property of CH 141

Chemical Property:

• Vapor Pressure: 3.94E-08mmHg at 25°C
• Boiling Point: 445.5°C at 760 mmHg
• Flash Point: 223.2°C
• PSA: 36.86000
• Density: 1.22g/cm³
• LogP: 2.09720

Purity/Quality:

98% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of CH 141

There total 2 articles about CH 141 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-phenyl-6-(toluene-4-sulfonyloxymethyl)-5,6-dihydro-2(4)H-[1,2,4]oxadiazine (56493-97-1) → 3-phenyl-6-(1,2,3,4-tetrahydro-2-isoquinolyl)-methyl-5,6-dihydro-4H-1,2,4-oxadiazine (78279-88-6)

Guidance literature:

With potassium carbonate; In chlorobenzene;

Reference yield:

3-phenyl-6-mesyloxymethyl-5,6-dihydro-4H-1,2,4-oxadiazine → 3-phenyl-6-(1,2,3,4-tetrahydro-2-isoquinolyl)-methyl-5,6-dihydro-4H-1,2,4-oxadiazine (78279-88-6)

Guidance literature:

Reference yield:

3-phenyl-6-(1,2,3,4-tetrahydro-2-isoquinolyl)-methyl-5,6-dihydro-4H-1,2,4-oxadiazine (78279-88-6) → 3-phenyl-4-benzoyl-6-(1,2,3,4-tetrahydro-2-isoquinolyl)-methyl-5,6-dihydro-1,2,4-oxadiazine + benzoyl chloride (98-88-4)

Guidance literature:

upstream raw materials:

3-phenyl-6-(toluene-4-sulfonyloxymethyl)-5,6-dihydro-2⁽⁴⁾H-[1,2,4]oxadiazine

Downstream raw materials:

benzoyl chloride