Dimethyl (3-aminophenyl)phosphonate

Base Information

Chemical Name:Dimethyl (3-aminophenyl)phosphonate
CAS No.:89277-83-8
Molecular Formula:C8H12NO3P
Molecular Weight:201.162
Hs Code.:
ChEMBL ID:CHEMBL351575
DSSTox Substance ID:DTXSID50537795
Wikidata:Q82412904

Synonyms:dimethyl (3-aminophenyl)phosphonate;89277-83-8;CHEMBL351575;DTXSID50537795

Suppliers and Price of Dimethyl (3-aminophenyl)phosphonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of Dimethyl (3-aminophenyl)phosphonate

Chemical Property:

XLogP3:0.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:201.05548024
Heavy Atom Count:13
Complexity:202

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COP(=O)(C1=CC=CC(=C1)N)OC

Technology Process of Dimethyl (3-aminophenyl)phosphonate

There total 6 articles about Dimethyl (3-aminophenyl)phosphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 645-00-1
m-iodonitrobenzene

: 868-85-9
Dimethyl phosphite

: 1220125-41-6
monomethyl (3-aminophenyl)phosphonate

: 89277-83-8
dimethyl (3-aminophenyl)phosphonate

Guidance literature:: m-iodonitrobenzene; Dimethyl phosphite; With tetrakis(triphenylphosphine) palladium⁽⁰⁾; triethylamine; In acetone; at 70 ℃;

With palladium on activated charcoal; hydrogen; In methanol;

Reference yield:

: 89277-94-1
dimethyl (3-nitrophenyl)phosphonate

: 89277-83-8
dimethyl (3-aminophenyl)phosphonate

Guidance literature:: With hydrogen; palladium on activated charcoal; In methanol; under 2585.7 - 3102.9 Torr;
DOI:10.1021/jm00371a017

Reference yield:

: 5337-19-9
(m-nitrophenyl)phosphonic acid

: 89277-83-8
dimethyl (3-aminophenyl)phosphonate

Guidance literature:: Multi-step reaction with 3 steps

1: PCl₅

2: triethylamine / CH₂Cl₂ / 4 h / 25 °C

3: H₂ / 10percent Pd/C / methanol / 2585.7 - 3102.9 Torr

With phosphorus pentachloride; hydrogen; triethylamine; palladium on activated charcoal; In methanol; dichloromethane;
DOI:10.1021/jm00371a017