2-Cyano-6-hydroxypyridine

Base Information

Chemical Name:2-Cyano-6-hydroxypyridine
CAS No.:89324-17-4
Molecular Formula:C₆H₄N₂O
Molecular Weight:120.111
Hs Code.:2933399090
European Community (EC) Number:819-948-9
Nikkaji Number:J2.371.894D
Mol file:89324-17-4.mol

Synonyms:89324-17-4;2-CYANO-6-HYDROXYPYRIDINE;6-hydroxypicolinonitrile;6-oxo-1,6-dihydropyridine-2-carbonitrile;6-HYDROXYPYRIDINE-2-CARBONITRILE;1,6-dihydro-6-oxo-2-pyridinecarbonitrile;95907-04-3;6-oxo-1H-pyridine-2-carbonitrile;SCHEMBL1281155;SCHEMBL11758136;MFCD11036300;MFCD11044306;AKOS006344251;AKOS026738320;AB62925;SB21112;AS-50750;SY013218;CS-0045079;FT-0714069;EN300-118352;P11008;A861239

Suppliers and Price of 2-Cyano-6-hydroxypyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
6-Hydroxypyridine-2-carbonitrile
50mg
$ 220.00

Crysdot
6-Hydroxypicolinonitrile 95+%
1g
$ 508.00

Crysdot
6-Hydroxypicolinonitrile 95+%
5g
$ 1524.00

Chemenu
6-Hydroxypicolinonitrile 95%
5g
$ 1425.00

Chemenu
6-Hydroxypicolinonitrile 95%
1g
$ 475.00

American Custom Chemicals Corporation
6-HYDROXYPICOLINONITRILE 95.00%
5MG
$ 500.15

Alichem
6-Hydroxypyridine-2-carbonitrile
1g
$ 364.35

Alichem
6-Hydroxypyridine-2-carbonitrile
5g
$ 1092.92

Advanced Chemicals Intermediatesced Chemicals Intermediates
6-Oxo-1,6-dihydro-pyridine-2-carbonitrile 95%+
1g
$ 862.75

Acints
6-Oxo-1,6-dihydro-pyridine-2-carbonitrile 95%+
1g
$ 862.75

Total 11 raw suppliers

Chemical Property of 2-Cyano-6-hydroxypyridine

Chemical Property:

Vapor Pressure:3.87E-05mmHg at 25°C
Boiling Point:352.3oC at 760 mmHg
Flash Point:166.9oC
PSA：56.65000
Density:1.27g/cm3
LogP:0.24658
XLogP3:0.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:120.032362755
Heavy Atom Count:9
Complexity:241

Purity/Quality:

97% ^*data from raw suppliers

6-Hydroxypyridine-2-carbonitrile ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=O)NC(=C1)C#N

Technology Process of 2-Cyano-6-hydroxypyridine

There total 6 articles about 2-Cyano-6-hydroxypyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 83621-01-6
2-cyano-6-methoxypyridine

: 89324-17-4,95907-04-3
6-Oxo-1,6-dihydropyridine-2-carbonitrile

Guidance literature:: With chloro-trimethyl-silane; sodium iodide; In acetonitrile;
DOI:10.1055/s-2001-14592

Reference yield:

: 1314968-34-7
1,6-dihydro-6-methoxypyridine-2-carbonitrile

: 89324-17-4,95907-04-3
6-Oxo-1,6-dihydropyridine-2-carbonitrile

Guidance literature:: With chloro-trimethyl-silane; water; sodium iodide; In acetonitrile; at 0 - 65 ℃; for 60h;

Reference yield:

: 626-05-1
2,6-Dibromopyridine

: 89324-17-4,95907-04-3
6-Oxo-1,6-dihydropyridine-2-carbonitrile

Guidance literature:: Multi-step reaction with 3 steps

1.1: 73 percent / sodium methoxide / 25 h / 62 °C

2.1: dimethylformamide / 48 h / 150 °C

2.2: 62 percent / FeCl₃*6H₂O; aq. HCl / dimethylformamide / 0.42 h / 80 °C

3.1: 82 percent / TMSCl; NaI / acetonitrile / 6 h / 80 °C

With chloro-trimethyl-silane; sodium methylate; sodium iodide; In N,N-dimethyl-formamide; acetonitrile;