Nonaethylene glycol

Base Information

• Chemical Name: Nonaethylene glycol
• CAS No.: 3386-18-3
• Molecular Formula: C18H38 O10
• Molecular Weight: 414.494
• Hs Code.: 2909499000
• European Community (EC) Number: 222-206-1
• DSSTox Substance ID: DTXSID10187492
• Nikkaji Number: J42.480C
• Wikidata: Q27120377
• Metabolomics Workbench ID: 56348
• Mol file: 3386-18-3.mol

Synonyms:NONAETHYLENE GLYCOL;3386-18-3;3,6,9,12,15,18,21,24-Octaoxahexacosane-1,26-diol;HO-PEG9-OH;2-[2-[2-[2-[2-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol;EINECS 222-206-1;C18H38O10;BRN 1804294;AI3-01837;CHEBI:39784;MFCD00698692;4-01-00-02409 (Beilstein Handbook Reference);1icj;PEG9;Epitope ID:159256;PEG-9;SCHEMBL269586;AMY4488;DTXSID10187492;BCP29446;AKOS015839828;C18-H38-O10;AS-67676;BP-22017;LS-96813;SY045924;HY-116899;CS-0066779;FT-0634814;N0698;S10648;EN300-7403031;A924507;J-523744;Q27120377

Chemical Property of Nonaethylene glycol

Chemical Property:

• Melting Point: 24.0-25.2 °C
• Refractive Index: 1.46
• Boiling Point: 506.2°Cat760mmHg
• PKA: 14.06±0.10(Predicted)
• Flash Point: 260°C
• PSA: 114.30000
• Density: 1.115g/cm³
• LogP: -0.89620
• Storage Temp.: 2-8°C
• XLogP3: -2.3
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 10
• Rotatable Bond Count: 25
• Exact Mass: 414.24649740
• Heavy Atom Count: 28
• Complexity: 245

Purity/Quality:

99% ^*data from raw suppliers

HO-PEG9-OH ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(COCCOCCOCCOCCOCCOCCOCCOCCO)O
• Description: Nonaethylene glycol is a polymer consisting of ethylene glycol repeating units and terminal hydroxyl groups. The ethylene glycol units have high water solubility properties. The hydroxyl groups can react in order to further derivatize the compound.
• Uses: HO-PEG9-OH is used as a reactant in the selective inhibition of human brain tumor cells through quantum-dot-based siRNA delivery.

Technology Process of Nonaethylene glycol

There total 35 articles about Nonaethylene glycol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

C32H50O10 (105891-55-2) → nonaethylene glycol (3386-18-3)

Guidance literature:

With hydrogen; palladium on activated charcoal; In methanol; at 60 ℃; for 1.5h; under 75006 Torr;

Reference yield: 92.0%

1,1,1,30,30,30-hexaphenyl-2,5,8,11,14,17,20,23,26,29-decaaoxatricontane (246832-16-6) → nonaethylene glycol (3386-18-3)

Guidance literature:

With hydrogen; palladium on activated charcoal; In dichloromethane; at 20 ℃; for 48h; under 38000 Torr;

DOI:10.1021/jo990620m

Reference yield: 91.0%

nonaethylene glycol bis(allyl ether) → nonaethylene glycol (3386-18-3)

Guidance literature:

With water; toluene-4-sulfonic acid; palladium on activated charcoal; In methanol; Heating;

DOI:10.1055/s-2004-816007

upstream raw materials:

1,20-dichloro-3,6,9,12,15,18-hexaoxatetradecane

ethylene glycol

1,2-bis(2-chloroethoxy)ethane

2,2'-[1,2-ethanediylbis(oxy)]bisethanol

Downstream raw materials:

51-Crown-17

Nonaethylene glycol ditosylate

3,6,9,12,15,18,21,24,27,30,33,36,39,42,45,48,51-heptadecaoxa-tripentacontane-1,53-diol

α-hydro, ω-hydroxyheptacosa(oxyethylene)