Technology Process of 2-Cyclohexene-1-acetic acid, 6-methyl-3-(phenylthio)-, methyl ester,
cis-
There total 12 articles about 2-Cyclohexene-1-acetic acid, 6-methyl-3-(phenylthio)-, methyl ester,
cis- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
water; lithium chloride;
In
dimethyl sulfoxide;
at 120 ℃;
for 12h;
DOI:10.1021/jo00186a033
- Guidance literature:
-
With
disodium hydrogenphosphate; sodium amalgam;
In
methanol;
for 2h;
Ambient temperature;
DOI:10.1021/jo00186a033
- Guidance literature:
-
Multi-step reaction with 10 steps
1: N-chlorosuccinimide / CCl4 / 13 h / 0 °C
2: 57 percent / NEt3 / CCl4 / 0 °C
3: hydroquinone / p-toluenesulfonic acid / toluene / 48 h / 80 °C
4: 63 percent / hydroquinone / toluene / 27 h / Ambient temperature
5: 78 percent / NaBH4 / toluene; methanol / 1 h / -23 °C
6: triethylamine / CH2Cl2 / 0.25 h / -10 °C
7: LAH / tetrahydrofuran / 0.5 h / Ambient temperature
8: 96 percent / 4-(dimethylamino)pyridine / CH2Cl2 / 0.08 h / 0 °C
9: 72 percent / Pd(diphos)2 / 1,2-dimethoxy-ethane / 0.5 h / 80 °C
10: 78 percent / H2O, LiCl / dimethylsulfoxide / 12 h / 120 °C
With
dmap; sodium tetrahydroborate; N-chloro-succinimide; lithium aluminium tetrahydride; water; triethylamine; hydroquinone; lithium chloride;
bis[1,2-bis(diphenylphosphino)ethane]palladium(0); toluene-4-sulfonic acid;
In
tetrahydrofuran; methanol; tetrachloromethane; 1,2-dimethoxyethane; dichloromethane; dimethyl sulfoxide; toluene;
DOI:10.1021/jo00186a033
