1-Phenyl-5-(p-bromophenyl)-3-hydroxy-4-carboxymethyl-2,5-dihydro-2-pyrrolone

Base Information

Chemical Name:1-Phenyl-5-(p-bromophenyl)-3-hydroxy-4-carboxymethyl-2,5-dihydro-2-pyrrolone
CAS No.:145510-85-6
Molecular Formula:C18H14 Br N O4
Molecular Weight:388.2121
Hs Code.:
DSSTox Substance ID:DTXSID50932625
Nikkaji Number:J529.723K
ChEMBL ID:CHEMBL1524618
Mol file:145510-85-6.mol

Synonyms:145510-85-6;1-Phenyl-5-(p-bromophenyl)-3-hydroxy-4-carboxymethyl-2,5-dihydro-2-pyrrolone;1H-Pyrrole-3-acetic acid, 2,5-dihydro-2-(4-bromophenyl)-4-hydroxy-5-oxo-1-phenyl-;2,5-Dihydro-2-(4-bromophenyl)-4-hydroxy-5-oxo-1-phenyl-1H-pyrrole-3-acetic acid;[2-(4-bromophenyl)-4-hydroxy-5-oxo-1-phenyl-2,5-dihydro-1H-pyrrol-3-yl]acetic acid;SMR000145414;Oprea1_527611;MLS000551489;CHEMBL1524618;DTXSID50932625;HMS2175J06;STL333515;AKOS022139337;NCGC00246315-01;LS-136577;[1-Phenyl-2-(4-bromophenyl)-4-hydroxy-5-oxo-3-pyrrolin-3-yl]acetic acid;[2-(4-Bromo-phenyl)-4-hydroxy-5-oxo-1-phenyl-2,5-dihydro-1H-pyrrol-3-yl]-acetic acid

Suppliers and Price of 1-Phenyl-5-(p-bromophenyl)-3-hydroxy-4-carboxymethyl-2,5-dihydro-2-pyrrolone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 1 raw suppliers

Chemical Property of 1-Phenyl-5-(p-bromophenyl)-3-hydroxy-4-carboxymethyl-2,5-dihydro-2-pyrrolone

Chemical Property:

Vapor Pressure:5.39E-14mmHg at 25°C
Boiling Point:573.6°Cat760mmHg
Flash Point:300.7°C
Density:1.622g/cm³
XLogP3:2.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:387.01062
Heavy Atom Count:24
Complexity:533

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)N2C(C(=C(C2=O)O)CC(=O)O)C3=CC=C(C=C3)Br

Technology Process of 1-Phenyl-5-(p-bromophenyl)-3-hydroxy-4-carboxymethyl-2,5-dihydro-2-pyrrolone

There total 5 articles about 1-Phenyl-5-(p-bromophenyl)-3-hydroxy-4-carboxymethyl-2,5-dihydro-2-pyrrolone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 145510-84-5
1-phenyl-5-(p-bromophenyl)-3-phenylamino-4-carboxymethyl-2,5-dihydro-2-pyrrolone

: 145510-85-6
1-phenyl-5-(p-bromophenyl)-3-hydroxy-4-carboxymethyl-2,5-dihydro-2-pyrrolone

Guidance literature:: With hydrogenchloride; for 24h; Ambient temperature;

Reference yield:

: 328-50-7
α-ketoglutaric acid

: 145510-85-6
1-phenyl-5-(p-bromophenyl)-3-hydroxy-4-carboxymethyl-2,5-dihydro-2-pyrrolone

Guidance literature:: Multi-step reaction with 2 steps

1: 77 percent / dioxane / 1.) heating 30 min, 2.) RT, 1 d

2: 84 percent / conc. aq. HCl / 24 h / Ambient temperature

With hydrogenchloride; In 1,4-dioxane;
DOI:10.1007/BF00819965

Reference yield:

: 62-53-3
aniline

: 145510-85-6
1-phenyl-5-(p-bromophenyl)-3-hydroxy-4-carboxymethyl-2,5-dihydro-2-pyrrolone

Guidance literature:: Multi-step reaction with 2 steps

1: 77 percent / dioxane / 1.) heating 30 min, 2.) RT, 1 d

2: 84 percent / conc. aq. HCl / 24 h / Ambient temperature

With hydrogenchloride; In 1,4-dioxane;
DOI:10.1007/BF00819965