Hexadecanoic acid, 4-methoxyphenyl ester

Base Information

• Chemical Name: Hexadecanoic acid, 4-methoxyphenyl ester
• CAS No.: 90149-62-5
• Molecular Formula: C23H38O3
• Molecular Weight: 362.553
• Mol file: 90149-62-5.mol

Synonyms:

Chemical Property of Hexadecanoic acid, 4-methoxyphenyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Hexadecanoic acid, 4-methoxyphenyl ester

There total 2 articles about Hexadecanoic acid, 4-methoxyphenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

4-methoxy-phenol (150-76-5) + 1-hexadecylcarboxylic acid (57-10-3) → 4-methoxyphenyl palmitate (90149-62-5)

Guidance literature:

1-hexadecylcarboxylic acid; With (E)-ethyl 2-cyano-2-(2-nitrophenylsulfonyloxyimino)acetate; N-ethyl-N,N-diisopropylamine; In dichloromethane; at 25 ℃;

4-methoxy-phenol; In dichloromethane; at 25 ℃; for 4h;

DOI:10.1021/jo500292m

Reference yield:

4-methoxy-phenol (150-76-5) + n-hexadecanoyl chloride (112-67-4) → 4-methoxyphenyl palmitate (90149-62-5)

Guidance literature:

With pyridine; diethyl ether; Behandeln unter Kuehlung;

DOI:10.1039/jr9420000659

Reference yield:

4-methoxyphenyl palmitate (90149-62-5) → 4-methoxy-phenol (150-76-5) + 1-hexadecylcarboxylic acid (57-10-3)

Guidance literature:

With sodium hydrogencarbonate; sodium carbonate; In water; dimethyl sulfoxide; at 45 ℃; Rate constant; effect of DMSO ratio;

DOI:10.1021/ja00311a075

upstream raw materials:

4-methoxy-phenol

n-hexadecanoyl chloride

1-hexadecylcarboxylic acid

Downstream raw materials:

4-methoxy-phenol

1-hexadecylcarboxylic acid

Refernces

• 1、 Saturnino, Carmela,Petrosino, Stefania,Ligresti, Alessia,Palladino, Chiara,Martino, Giovanni De,Bisogno, Tiziana,Marzo, Vincenzo Di. "Synthesis and biological evaluation of new potential inhibitors of N-acylethanolamine hydrolyzing acid amidase". supporting information; experimental part. p. 1210 - 1213. Retrieved 2010/05/19.