Metsulfuron

Base Information

• Chemical Name: Metsulfuron
• CAS No.: 69635-63-8
• Molecular Formula: C14H16 Cl N3 O2
• Molecular Weight: 293.752
• Mol file: 69635-63-8.mol

Synonyms:Amipizone

Chemical Property of Metsulfuron

Chemical Property:

• PSA: 70.56000
• Density: 1.35g/cm³
• LogP: 1.94990

Purity/Quality:

AMIPIZONE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Metsulfuron

There total 4 articles about Metsulfuron which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

3-benzoyl>butyric acid (85221-91-6) → amipizone (69635-63-8)

Guidance literature:

With hydrazine hydrate; In ethanol; for 3h; Heating;

DOI:10.1021/jm00360a004

Reference yield: 54.0%

2-chloropropionyl chloride (7623-09-8) + 6-(4-aminophenyl)-4,5-dihydro-5-methyl-3(2H)-pyridazinone (36725-28-7) → amipizone (69635-63-8)

Guidance literature:

In tetrahydrofuran; for 6h; Heating;

DOI:10.1021/jm00360a004

Reference yield:

4-(4-aminophenyl)-3-methyl-4-oxobutanoic acid (42075-29-6) → amipizone (69635-63-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 36 percent / tetrahydrofuran / 6 h / Heating

2: 87 percent / hydrazine hydrate / ethanol / 3 h / Heating

With hydrazine hydrate; In tetrahydrofuran; ethanol;

DOI:10.1021/jm00360a004

upstream raw materials:

3-benzoyl>butyric acid

2-chloropropionyl chloride

6-(4-aminophenyl)-4,5-dihydro-5-methyl-3(2H)-pyridazinone

4-(4-aminophenyl)-3-methyl-4-oxobutanoic acid

Refernces

• 1、 -. "6-(p-Acylaminophenyl)-4,5-dihydropyridaz-3-ones and therapeutic agents containing said compounds". . . Retrieved 2008/06/13.