3-Ethoxythiophene-2-carboxylic acid

Base Information

Chemical Name:3-Ethoxythiophene-2-carboxylic acid
CAS No.:139926-23-1
Molecular Formula:C7H8 O3 S
Molecular Weight:172.205
Hs Code.:2934999090
DSSTox Substance ID:DTXSID90380606
Nikkaji Number:J446.168A
Wikidata:Q82170916
ChEMBL ID:CHEMBL1706414
Mol file:139926-23-1.mol

Synonyms:3-ethoxythiophene-2-carboxylic acid;139926-23-1;2-Thiophenecarboxylic acid, 3-ethoxy-;Maybridge1_003798;3-Ethoxythiophene-2-carboxylicacid;MLS000849966;SCHEMBL1840806;3-ethoxythiophene-2-carboxylate;CHEMBL1706414;HMS552E14;DTXSID90380606;FTKDCOINUAYGTC-UHFFFAOYSA-N;HMS2779P24;3-ethoxy-2-thiophenecarboxylic acid;2-Thiophenecarboxylicacid,3-ethoxy-;MFCD00205205;AKOS009157932;SMR000455984;TS-02343;CS-0163742;FT-0615641;EN300-251693;3-ethoxythiophene-2-carboxylic acid, AldrichCPR;A807601;Z1124714289

Suppliers and Price of 3-Ethoxythiophene-2-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-Ethoxythiophene-2-carboxylic acid
50mg
$ 60.00

SynQuest Laboratories
3-Ethoxythiophene-2-carboxylic acid
1 g
$ 160.00

Matrix Scientific
3-Ethoxythiophene-2-carboxylic acid 97%
1g
$ 119.00

Crysdot
3-Ethoxythiophene-2-carboxylic acid 97%
25g
$ 1944.00

Crysdot
3-Ethoxythiophene-2-carboxylic acid 97%
10g
$ 887.00

Crysdot
3-Ethoxythiophene-2-carboxylic acid 97%
5g
$ 466.00

Atlantic Research Chemicals
3-Ethoxythiophene-2-carboxylic acid 95%
1gm:
$ 60.09

Apolloscientific
3-Ethoxythiophene-2-carboxylic acid
1g
$ 145.00

American Custom Chemicals Corporation
3-ETHOXYTHIOPHENE-2-CARBOXYLIC ACID 95.00%
1G
$ 673.11

Alichem
3-Ethoxythiophene-2-carboxylic acid
10g
$ 886.05

Total 18 raw suppliers

Chemical Property of 3-Ethoxythiophene-2-carboxylic acid

Chemical Property:

Vapor Pressure:0.000363mmHg at 25°C
Melting Point:121-123°C
Boiling Point:305.3°Cat760mmHg
PKA:3.68±0.10(Predicted)
Flash Point:138.4°C
PSA：74.77000
Density:1.305g/cm³
LogP:1.84500
Storage Temp.:2-8°C
XLogP3:1.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:172.01941529
Heavy Atom Count:11
Complexity:149

Purity/Quality:

99%, ^*data from raw suppliers

3-Ethoxythiophene-2-carboxylic acid ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38-36
Safety Statements: 26-36/37/39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC1=C(SC=C1)C(=O)O
Uses 3-Ethoxythiophene-2-carboxylic acid is used as a pharmaceutical intermediate.

Technology Process of 3-Ethoxythiophene-2-carboxylic acid

There total 2 articles about 3-Ethoxythiophene-2-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 139926-22-0
methyl 3-ethoxythiophene-2-carboxylate

: 139926-23-1
3-Ethoxy-thiophene-2-carboxylic acid

Guidance literature:: With sodium hydroxide; Heating;
DOI:10.1002/ardp.19923250206

Reference yield:

: 5118-06-9
methyl 3-hydroxy-2-thiophenecarboxylate

: 139926-23-1
3-Ethoxy-thiophene-2-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 89 percent / 1) K₂CO₃ / acetone / 1) 10 min, 2) 5 h, reflux

2: 95 percent / 1M NaOH / Heating

With sodium hydroxide; potassium carbonate; In acetone;
DOI:10.1002/ardp.19923250206