3-Ethoxythiophene-2-carbonyl chloride

Base Information

Chemical Name:3-Ethoxythiophene-2-carbonyl chloride
CAS No.:139926-24-2
Molecular Formula:C7H7 Cl O2 S
Molecular Weight:190.65
Hs Code.:
DSSTox Substance ID:DTXSID10568601
Wikidata:Q82454903
Mol file:139926-24-2.mol

Synonyms:3-Ethoxythiophene-2-carbonyl chloride;139926-24-2;2-THIOPHENECARBONYL CHLORIDE, 3-ETHOXY-;SCHEMBL3063419;DTXSID10568601;FBAYKPYCNPDYQQ-UHFFFAOYSA-N;2-Thiophenecarbonylchloride,3-ethoxy-(9CI)

Suppliers and Price of 3-Ethoxythiophene-2-carbonyl chloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
3-Ethoxythiophene-2-carbonylchloride 95%
1g
$ 672.00

American Custom Chemicals Corporation
2-THIOPHENECARBONYL CHLORIDE, 3-ETHOXY- 95.00%
5MG
$ 503.87

Total 1 raw suppliers

Chemical Property of 3-Ethoxythiophene-2-carbonyl chloride

Chemical Property:

PSA：54.54000
LogP:2.52580
XLogP3:2.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:189.9855283
Heavy Atom Count:11
Complexity:151

Purity/Quality:: 3-Ethoxythiophene-2-carbonylchloride 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC1=C(SC=C1)C(=O)Cl

Technology Process of 3-Ethoxythiophene-2-carbonyl chloride

There total 3 articles about 3-Ethoxythiophene-2-carbonyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 139926-23-1
3-Ethoxy-thiophene-2-carboxylic acid

: 139926-24-2
3-ethoxythiophene-2-carbonyl chloride

Guidance literature:: With thionyl chloride; In N,N-dimethyl-formamide; benzene; for 0.25h; Heating;
DOI:10.1002/ardp.19923250206

Reference yield:

: 5118-06-9
methyl 3-hydroxy-2-thiophenecarboxylate

: 139926-24-2
3-ethoxythiophene-2-carbonyl chloride

Guidance literature:: Multi-step reaction with 3 steps

1: 89 percent / 1) K₂CO₃ / acetone / 1) 10 min, 2) 5 h, reflux

2: 95 percent / 1M NaOH / Heating

3: SOCl₂ / dimethylformamide; benzene / 0.25 h / Heating

With sodium hydroxide; thionyl chloride; potassium carbonate; In N,N-dimethyl-formamide; acetone; benzene;
DOI:10.1002/ardp.19923250206

Reference yield:

: 139926-22-0
methyl 3-ethoxythiophene-2-carboxylate

: 139926-24-2
3-ethoxythiophene-2-carbonyl chloride

Guidance literature:: Multi-step reaction with 2 steps

1: 95 percent / 1M NaOH / Heating

2: SOCl₂ / dimethylformamide; benzene / 0.25 h / Heating

With sodium hydroxide; thionyl chloride; In N,N-dimethyl-formamide; benzene;
DOI:10.1002/ardp.19923250206