Acetamide, 2-((1-(p-fluorobenzyl)-2-methyl-4-nitro-1H-imidazol-5-yl)thio)-

Base Information

Chemical Name:Acetamide, 2-((1-(p-fluorobenzyl)-2-methyl-4-nitro-1H-imidazol-5-yl)thio)-
CAS No.:77952-75-1
Molecular Formula:C₁₃H₁₃FN₄O₃S
Molecular Weight:324.336
Hs Code.:
DSSTox Substance ID:DTXSID10228617
Wikidata:Q83108642

Synonyms:BRN 5134560;Acetamide, 2-((1-(p-fluorobenzyl)-2-methyl-4-nitro-1H-imidazol-5-yl)thio)-;2-((1-(p-Fluorobenzyl)-2-methyl-4-nitro-1H-imidazol-5-yl)thio)acetamide;77952-75-1;C13H13FN4O3S;DTXSID10228617;C13-H13-F-N4-O3-S;LS-9597

Suppliers and Price of Acetamide, 2-((1-(p-fluorobenzyl)-2-methyl-4-nitro-1H-imidazol-5-yl)thio)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of Acetamide, 2-((1-(p-fluorobenzyl)-2-methyl-4-nitro-1H-imidazol-5-yl)thio)-

Chemical Property:

Vapor Pressure:1.14E-12mmHg at 25°C
Boiling Point:562.3°Cat760mmHg
Flash Point:293.9°C
Density:1.49g/cm³
XLogP3:2.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:5
Exact Mass:324.06923963
Heavy Atom Count:22
Complexity:415

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=NC(=C(N1CC2=CC=C(C=C2)F)SCC(=O)N)[N+](=O)[O-]

Technology Process of Acetamide, 2-((1-(p-fluorobenzyl)-2-methyl-4-nitro-1H-imidazol-5-yl)thio)-

There total 2 articles about Acetamide, 2-((1-(p-fluorobenzyl)-2-methyl-4-nitro-1H-imidazol-5-yl)thio)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 77952-62-6
3-(4-Fluoro-benzyl)-2-methyl-5-nitro-3H-imidazole-4-thiol; compound with ammonia

: 79-07-2
Chloroacetamide

: 77952-75-1
2-[3-(4-Fluoro-benzyl)-2-methyl-5-nitro-3H-imidazol-4-ylsulfanyl]-acetamide

Guidance literature:: In methanol; water; Heating; 1.) reflux, 6-7 h, 2.) overnight;
DOI:10.1007/BF01149151

Reference yield:

: 68019-72-7
5-bromo-1-(4-fluoro-benzyl)-2-methyl-4-nitro-1H-imidazole

: 77952-75-1
2-[3-(4-Fluoro-benzyl)-2-methyl-5-nitro-3H-imidazol-4-ylsulfanyl]-acetamide

Guidance literature:: Multi-step reaction with 2 steps

1: 69 percent / H₂S, ethanolic NH₃ / dimethylformamide / 0.17 h

2: 73 percent / methanol; H₂O / Heating; 1.) reflux, 6-7 h, 2.) overnight

With hydrogen sulfide; ammonia; In methanol; water; N,N-dimethyl-formamide;
DOI:10.1007/BF01149151