4-(5-Methyl-pyridin-2-yl)-piperazine-1-carboxylic acid tert-butyl ester, 98+% C15H23N3O2, MW: 277.36

Base Information

Chemical Name:4-(5-Methyl-pyridin-2-yl)-piperazine-1-carboxylic acid tert-butyl ester, 98+% C15H23N3O2, MW: 277.36
CAS No.:907208-89-3
Molecular Formula:C15H23N3O2
Molecular Weight:277.36200
Hs Code.:
Mol file:907208-89-3.mol

Synonyms:1-(tert-butyloxycarbonyl)-4-(5-methylpyridin-2-yl)piperazine;4-(5-methylpyridin-2-yl)piperazine-1-carboxylic acid tert-butyl ester;tert-butyl 4-(5-methyl-2-pyridyl)piperazinecarboxylate;

Suppliers and Price of 4-(5-Methyl-pyridin-2-yl)-piperazine-1-carboxylic acid tert-butyl ester, 98+% C15H23N3O2, MW: 277.36

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Chemenu
tert-butyl4-(5-methylpyridin-2-yl)piperazine-1-carboxylate 95%
1g
$ 599.00

American Custom Chemicals Corporation
TERT-BUTYL-4-(5-METHYL-PYRIDIN-2-YL)-PIPERAZINE-1-CARBOXYLATE 95.00%
5MG
$ 501.27

Total 7 raw suppliers

Chemical Property of 4-(5-Methyl-pyridin-2-yl)-piperazine-1-carboxylic acid tert-butyl ester, 98+% C15H23N3O2, MW: 277.36

Chemical Property:

PSA：45.67000
Density:1.111
LogP:2.45000

Purity/Quality:

99% ^*data from raw suppliers

tert-butyl4-(5-methylpyridin-2-yl)piperazine-1-carboxylate 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 4-(5-Methyl-pyridin-2-yl)-piperazine-1-carboxylic acid tert-butyl ester, 98+% C15H23N3O2, MW: 277.36

There total 4 articles about 4-(5-Methyl-pyridin-2-yl)-piperazine-1-carboxylic acid tert-butyl ester, 98+% C15H23N3O2, MW: 277.36 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 72093-07-3
2-methyl-5-chloropyridine

: 57260-71-6
1-t-Butoxycarbonylpiperazine

: 907208-89-3
1-(tert-butyloxycarbonyl)-4-(5-methylpyridin-2-yl)piperazine

Guidance literature:: With 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; sodium t-butanolate; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; In toluene; at 70 ℃; for 12h; Inert atmosphere;

Reference yield: 97.0%

: 18368-64-4
2-chloro-5-methylpyridine

: 57260-71-6
1-t-Butoxycarbonylpiperazine

: 907208-89-3
1-(tert-butyloxycarbonyl)-4-(5-methylpyridin-2-yl)piperazine

Guidance literature:: With sodium t-butanolate; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; In toluene; at 70 ℃; for 12h;

Reference yield: 80.0%

: 3510-66-5
2-Bromo-5-methylpyridine

: 57260-71-6
1-t-Butoxycarbonylpiperazine

: 907208-89-3
1-(tert-butyloxycarbonyl)-4-(5-methylpyridin-2-yl)piperazine

Guidance literature:: With palladium diacetate; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; sodium t-butanolate; In toluene; at 70 ℃; for 12h; Inert atmosphere; Glovebox;
DOI:10.1021/jacs.0c13415