72093-07-3 Usage
Uses
Used in Pharmaceutical Industry:
5-Chloro-2-picoline is used as an intermediate for the synthesis of pyridine derivatives, which are essential in the production of a wide variety of pharmaceuticals. Its unique chemical properties contribute to the development of new drugs and medications.
Used in Agrochemical Industry:
In the agrochemical sector, 5-chloro-2-picoline is utilized in the manufacturing of herbicides and pesticides. Its role in the synthesis of these agricultural chemicals helps to improve crop protection and yield.
Used in Organic Synthesis:
5-Chloro-2-picoline is used as a reagent in organic synthesis, enabling the creation of various organic compounds. Its versatility in this field allows for the development of new chemical entities with potential applications in different industries.
Used as a Solvent in Industrial Processes:
5-chloro-2-picoline also serves as a solvent in various industrial processes. Its properties make it suitable for use in a range of applications, contributing to the efficiency and effectiveness of these processes.
Check Digit Verification of cas no
The CAS Registry Mumber 72093-07-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,2,0,9 and 3 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 72093-07:
(7*7)+(6*2)+(5*0)+(4*9)+(3*3)+(2*0)+(1*7)=113
113 % 10 = 3
So 72093-07-3 is a valid CAS Registry Number.
InChI:InChI=1/C6H6ClN/c1-5-2-3-6(7)4-8-5/h2-4H,1H3
72093-07-3Relevant academic research and scientific papers
Goldfogel, Matthew J.,Jamison, Christopher R.,Savage, Scott A.,Haley, Matthew W.,Mukherjee, Subha,Sfouggatakis, Chris,Gujjar, Manjunath,Mohan, Jayaraj,Rakshit, Souvik,Vaidyanathan, Rajappa
, p. 624 - 634 (2022)
The development and implementation of two process syntheses to provide BMS-986224, an agonist of the APJ receptor, are reported. The first-generation synthesis of BMS-986224 relied on a key enamine cyclization to construct the pyridone core; however, the overall efficiency of this route was limited by the linear synthesis of the hindered biaryl pyridone. This lack of convergence is solved in a second-generation route that minimizes low-temperature lithiation chemistry, replaces costly Pd coupling with scalable nucleophilic arylation, and reduces step count. The improved synthesis was enabled by a new Negishi coupling method that addresses limitations of the Suzuki-Miyaura literature for tetra-ortho-substituted biaryl pyridones.
