glutathionyldopa

Base Information

• Chemical Name: glutathionyldopa
• CAS No.: 55136-58-8
• Molecular Formula: C₁₉H₂₆N₄O₁₀S
• Molecular Weight: 502.502
• Mol file: 55136-58-8.mol

Synonyms:Glycine,N-[S-[5-(2-amino-2-carboxyethyl)-2,3-dihydroxyphenyl]-N-L-g-glutamyl-L-cysteinyl]-, (S)-;5-S-glutathionyl-DOPA; Glutathione-DOPA

Chemical Property of glutathionyldopa

Chemical Property:

• Vapor Pressure: 3.85E-30mmHg at 25°C
• Boiling Point: 842.4°C at 760 mmHg
• Flash Point: 463.3°C
• Density: 1.64g/cm³

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of glutathionyldopa

There total 5 articles about glutathionyldopa which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 53.2%

GLUTATHIONE (70-18-8) + D-Dopa (5796-17-8,90638-38-3) → 5-S-G-D-D (55136-58-8)

Guidance literature:

With potassium phosphate buffer; mushroom tyrosinase; Ambient temperature;

DOI:10.1248/cpb.47.777

Reference yield: 50.0%

GLUTATHIONE (70-18-8) + levodopa (59-92-7,90638-38-3) → 5-S-G-L-D (55136-58-8)

Guidance literature:

With potassium phosphate buffer; mushroom tyrosinase; Ambient temperature;

DOI:10.1248/cpb.47.777

Reference yield:

D-Dopa (5796-17-8,90638-38-3) → 5-S-G-D-D (55136-58-8)

Guidance literature:

Multi-step reaction with 2 steps

1: mushroom tyrosinase

DOI:10.1248/cpb.46.1950

upstream raw materials:

GLUTATHIONE

L-dopaquinone

levodopa

o-dopaquinone

Refernces

• 1、 Zheng, Zhe-Bin,Nagai, Sachie,Iwanami, Naoko,Kobayashi, Ayako,Hijikata, Mariko,Natori, Shunji,Sankawa, Ushio. "Selective inhibition of Src protein tyrosine kinase by analogues of 5- S-glutathionyl-β-alanyl-L-dopa". . p. 1950 - 1951. Retrieved 2007/10/03.