Methanesulfonamide, N-(4-(1H-imidazol-1-ylacetyl)phenyl)-

Base Information

Chemical Name:Methanesulfonamide, N-(4-(1H-imidazol-1-ylacetyl)phenyl)-
CAS No.:77234-67-4
Molecular Formula:C12H13 N3 O3 S
Molecular Weight:279.32
Hs Code.:
DSSTox Substance ID:DTXSID40227971
Wikidata:Q83107813
ChEMBL ID:CHEMBL436035
Mol file:77234-67-4.mol

Synonyms:BRN 4510490;N-(4-(Methanesulfonamido)phenacyl)imidazole;77234-67-4;N-(4-(1H-Imidazol-1-ylacetyl)phenyl)methanesulfonamide;Methanesulfonamide, N-(4-(1H-imidazol-1-ylacetyl)phenyl)-;CHEMBL436035;SCHEMBL9663725;DTXSID40227971;LS-90138

Suppliers and Price of Methanesulfonamide, N-(4-(1H-imidazol-1-ylacetyl)phenyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
N-(4-(1H-IMIDAZOL-1-YLACETYL)PHENYL)METHANESULFONAMIDE 95.00%
5MG
$ 500.37

Total 3 raw suppliers

Chemical Property of Methanesulfonamide, N-(4-(1H-imidazol-1-ylacetyl)phenyl)-

Chemical Property:

Vapor Pressure:3.8E-12mmHg at 25°C
Boiling Point:550°C at 760 mmHg
Flash Point:286.4°C
PSA：89.44000
Density:1.35g/cm³
LogP:2.29130
XLogP3:0.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:5
Exact Mass:279.06776246
Heavy Atom Count:19
Complexity:410

Purity/Quality:

99% ^*data from raw suppliers

N-(4-(1H-IMIDAZOL-1-YLACETYL)PHENYL)METHANESULFONAMIDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CS(=O)(=O)NC1=CC=C(C=C1)C(=O)CN2C=CN=C2

Technology Process of Methanesulfonamide, N-(4-(1H-imidazol-1-ylacetyl)phenyl)-

There total 2 articles about Methanesulfonamide, N-(4-(1H-imidazol-1-ylacetyl)phenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 37.0%

: 124-63-0
methanesulfonyl chloride

: 73932-42-0
1-(4-aminophenyl)-2-(1H-imidazol-1-yl)ethanone

: 77234-67-4
N-<4-<2-(1H-imidazol-1-yl)-1-oxoethyl>phenyl>methanesulfonamide

Guidance literature:: With pyridine; In N,N,N,N,N,N-hexamethylphosphoric triamide; at 80 ℃; for 6h;
DOI:10.1021/jm00138a017

Reference yield:

: 77234-68-5
2-(1H-imidazol-1-yl)-1-(4-nitrophenyl)ethanone hydrochloride

: 77234-67-4
N-<4-<2-(1H-imidazol-1-yl)-1-oxoethyl>phenyl>methanesulfonamide

Guidance literature:: Multi-step reaction with 2 steps

1: 54 percent / H₂ / 5percent Pd/C / methanol

2: 37 percent / pyridine / hexamethylphosphoric acid triamide / 6 h / 80 °C

With pyridine; hydrogen; palladium on activated charcoal; In methanol; N,N,N,N,N,N-hexamethylphosphoric triamide;
DOI:10.1021/jm00138a017

Reference yield: 90.0%

: 77234-67-4
N-<4-<2-(1H-imidazol-1-yl)-1-oxoethyl>phenyl>methanesulfonamide

: 97163-52-5
(+/-)-N-<4-<1-hydroxy-2-(1H-imidazol-1-yl)-ethyl>phenyl>methanesulfonamide hydrochloride

Guidance literature:: With hydrogenchloride; hydrogen; palladium on activated charcoal; In water; for 24h; under 2585.7 Torr; Ambient temperature;
DOI:10.1021/jm00387a020