7,7-Dimethyl-(5Z,8Z)-eicosadienoic acid

Base Information

Chemical Name:7,7-Dimethyl-(5Z,8Z)-eicosadienoic acid
CAS No.:89560-01-0
Molecular Formula:C₂₂H₄₀O₂
Molecular Weight:336.558
Hs Code.:
DSSTox Substance ID:DTXSID401017363
Wikidata:Q76296842
Metabolomics Workbench ID:308
ChEMBL ID:CHEMBL1323529
Mol file:89560-01-0.mol

Synonyms:7,7-dimethyl-5,8-eicosadienoic acid;7,7-dimethyl-EDA;7,7-dimethyl-eicosadienoic acid

Suppliers and Price of 7,7-Dimethyl-(5Z,8Z)-eicosadienoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
7,7-DimethyleicosadienoicAcid(DEDA)
10mg
$ 65.00

Sigma-Aldrich
7,7-Dimethyl-(5Z,8Z)-eicosadienoic acid ≥95%
10mg
$ 153.00

American Custom Chemicals Corporation
7,7-DIMETHYLEICOSADIENOIC ACID 95.00%
10MG
$ 208.95

Alfa Aesar
7,7-Dimethyleicosadienoic acid, 99%
10mg
$ 130.00

Total 3 raw suppliers

Chemical Property of 7,7-Dimethyl-(5Z,8Z)-eicosadienoic acid

Chemical Property:

Vapor Pressure:1.38E-09mmHg at 25°C
Boiling Point:456.1°C at 760 mmHg
Flash Point:352.7°C
PSA：37.30000
Density:0.9g/cm³
LogP:7.30080
Storage Temp.:−20°C
XLogP3:8.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:16
Exact Mass:336.302830514
Heavy Atom Count:24
Complexity:353

Purity/Quality:

98%Min ^*data from raw suppliers

7,7-DimethyleicosadienoicAcid(DEDA) ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Statements: 23/24/25-36/38-39/23/24/25
Safety Statements: 7-24-36/37-45

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:CCCCCCCCCCCC=CC(C)(C)C=CCCCC(=O)O
Isomeric SMILES:CCCCCCCCCCC/C=C\C(C)(C)/C=C\CCCC(=O)O
Uses 7,7-Dimethyleicosadienoic Acid (DEDA) is an inhibitor of PLA2, sPLA2, and 5-LO.

Technology Process of 7,7-Dimethyl-(5Z,8Z)-eicosadienoic acid

There total 9 articles about 7,7-Dimethyl-(5Z,8Z)-eicosadienoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

aqueous potassium hydroxide: aqueous potassium hydroxide

: hexane-diethyl ether

: 15510-55-1
dodecyltriphenylphosphonium bromide

: 89560-00-9
methyl 7,7-dimethyl-8-oxo-5(Z)-octenoate

: 89560-02-1
methyl 7,7-dimethyleicosa-5Z,8Z-dienoate

: 89560-01-0
7,7-dimethyl-(5Z,8Z)-eicosadienoic acid

Guidance literature:: With n-butyllithium; In tetrahydrofuran; methanol; tetrahydrofuran-hexamethylphosphorictriamide; hexane;

Reference yield:

: 89560-02-1
methyl 7,7-dimethyleicosa-5Z,8Z-dienoate

: 89560-01-0
7,7-dimethyl-(5Z,8Z)-eicosadienoic acid

Guidance literature:: With potassium hydroxide; In methanol;
DOI:10.1016/S0040-4039(00)94063-2

Reference yield:

: 66582-32-9
3-(benzyloxy)-2,2-dimethylpropan-1-ol

: 89560-01-0
7,7-dimethyl-(5Z,8Z)-eicosadienoic acid

Guidance literature:: Multi-step reaction with 7 steps

1: 66 percent / pyridinium chlorochromate

2: 53 percent / potassium t-butoxide

3: Na / liquid ammonia

5: pyridinium chlorochromate

6: 61 percent / Bu-Li / tetrahydrofuran; hexamethylphosphoric acid triamide / -78 °C

7: aq. KOH / methanol

With potassium hydroxide; n-butyllithium; potassium tert-butylate; sodium; pyridinium chlorochromate; In tetrahydrofuran; methanol; N,N,N,N,N,N-hexamethylphosphoric triamide; ammonia;
DOI:10.1016/S0040-4039(00)94063-2