Adenosine triphosphate adenosine monophosphate adenosine monophosphate

Base Information

• Chemical Name: Adenosine triphosphate adenosine monophosphate adenosine monophosphate
• CAS No.: 65954-93-0
• Molecular Formula: C30H40N15O25P5
• Molecular Weight: 1165.5929
• Mol file: 65954-93-0.mol

Synonyms:ppp5'A2'p5'A2'p5'A;pppA2'p5'A2'p5'A;5'-Triphosphoadenylyl(2'-5')adenylyl(2'-5')adenosine;adenylyl-(5'->2')-adenylyl-(5'->2')-O5'-tetrahydroxy[1]triphosphoryl-adenosine;5'-triphosphate of 2',5'-triadenylate;

Chemical Property of Adenosine triphosphate adenosine monophosphate adenosine monophosphate

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• PSA: 637.86000
• Density: 2.61g/cm³
• LogP: -1.52020

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Adenosine triphosphate adenosine monophosphate adenosine monophosphate

There total 10 articles about Adenosine triphosphate adenosine monophosphate adenosine monophosphate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

MopA2'p5'A2'p5'A triethylammonium salt (95314-15-1) → pppA2'p5'A2'p5'A (65954-93-0)

Guidance literature:

With tri(n-butyl)ammonium pyrophosphate; In N,N-dimethyl-formamide; for 72h; Ambient temperature;

DOI:10.1021/jo00209a014

Reference yield: 55.5%

ATP (56-65-5,896506-78-8) → pppA2'p5'A2'p5'A (65954-93-0) + C40H52N20O31P6 (65954-95-2) + C50H64N25O37P7 (65954-96-3) + C60H76N30O43P8 (84295-89-6) + 5'-O-triphosphoadenylyl-(2'->5')-adenosine (65954-94-1)

Guidance literature:

With 1,4-dithio-D,L-threitol; porcine oligoadenylate synthetase 1; magnesium chloride; at 30 ℃; for 2h; pH=7.5; aq. buffer; Enzymatic reaction;

DOI:10.1016/j.antiviral.2010.06.003

Reference yield: 48.0%

p5'A2'p5'A2'p5'A (61172-40-5) → pppA2'p5'A2'p5'A (65954-93-0) + 5'-diphosphate of 2',5'-triadenylate (76991-64-5)

Guidance literature:

With phosphorotriimidazolide; magnesium chloride; at 22 ℃; for 168h; N-ethylmorpholine buffer (pH 7.0);

DOI:10.1016/S0040-4039(00)74092-5

upstream raw materials:

p5'A2'p5'A2'p5'A

C₈₆H₉₂Br₃Cl₂N₁₆O₃₀P₃

Phosphoric acid (1R,2R)-1-(6-amino-purin-9-yl)-3-{[(2R,3R,4R,5R)-2-(6-amino-purin-9-yl)-4-hydroxy-5-phosphonooxymethyl-tetrahydro-furan-3-yloxy]-hydroxy-phosphoryloxy}-2-hydroxy-propyl ester (2R,3R)-3-(6-amino-purin-9-yl)-2,3-dihydroxy-propyl ester

MopA₂'p5'A₂'p5'A triethylammonium salt

Downstream raw materials:

adenylyl(2'-5')adenylyl(2'-5')adenosine

Refernces

• 1、 Ikehara et al.. "". . p. 3677. Retrieved 1979.
• 2、 Kalinichenko, Elena N.,Podkopaeva, Tatjana L.,Poopeiko, Nicolai E.,Kelve, Merike,Saarma, Mart,et al.. "Role of the stereochemistry of 3'-fluoro-3'-deoxy analogues of 2-5A in binding to and activation of mouse RNase L". . p. 43 - 50. Retrieved 2007/10/02.