5'-diphosphate of 2',5'-triadenylate

Base Information

• Chemical Name: 5'-diphosphate of 2',5'-triadenylate
• CAS No.: 76991-64-5
• Molecular Formula: C₃₀H₃₉N₁₅O₂₂P₄
• Molecular Weight: 1085.62
• Mol file: 76991-64-5.mol

Synonyms:5'-diphosphate of 2',5'-triadenylate

Chemical Property of 5'-diphosphate of 2',5'-triadenylate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 5'-diphosphate of 2',5'-triadenylate

There total 2 articles about 5'-diphosphate of 2',5'-triadenylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 48.0%

p5'A2'p5'A2'p5'A (61172-40-5) → pppA2'p5'A2'p5'A (65954-93-0) + 5'-diphosphate of 2',5'-triadenylate (76991-64-5)

Guidance literature:

With phosphorotriimidazolide; magnesium chloride; at 22 ℃; for 168h; N-ethylmorpholine buffer (pH 7.0);

DOI:10.1016/S0040-4039(00)74092-5

Reference yield:

ATP (56-65-5,896506-78-8) → ppA2'p5'A (81410-37-9) + C40H51N20O28P5 (81410-35-7) + 5'-diphosphate of 2',5'-triadenylate (76991-64-5) + adenosine 5'-diphosphate (58-64-0,905904-58-7)

Guidance literature:

ATP; With 1,4-dithio-D,L-threitol; porcine oligoadenylate synthetase 1; magnesium chloride; at 30 ℃; for 2h; pH=7.5; aq. buffer; Enzymatic reaction;

With vaccinia virus capping enzyme; at 37 ℃; for 2h; Enzymatic reaction;

DOI:10.1016/j.antiviral.2010.06.003

upstream raw materials:

p5'A2'p5'A2'p5'A

ATP