3-Ethynyl-1-methylpiperidine

Base Information

Chemical Name:3-Ethynyl-1-methylpiperidine
CAS No.:91324-40-2
Molecular Formula:C8H13N
Molecular Weight:
Hs Code.:
DSSTox Substance ID:DTXSID80533184

Synonyms:3-Ethynyl-1-methylpiperidine;91324-40-2;3-ETHYNYL-1-METHYL-PIPERIDINE;SCHEMBL2600237;DTXSID80533184;EN300-1067387

Suppliers and Price of 3-Ethynyl-1-methylpiperidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 3-Ethynyl-1-methylpiperidine

Chemical Property:

XLogP3:1.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:123.104799419
Heavy Atom Count:9
Complexity:131

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1CCCC(C1)C#C

Technology Process of 3-Ethynyl-1-methylpiperidine

There total 2 articles about 3-Ethynyl-1-methylpiperidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 6965-62-4
3-acetyl-1-methylpyridinium iodide

: 91324-40-2
1-Methyl-3-ethynylpiperidine

Guidance literature:: Multi-step reaction with 2 steps

1: H₂ / PtO₂ / aq. ethanol / 7 h / 70 °C

2: 1.) POCl₃, PCl₅, 2.) sodamide / 1.) 90 deg C, 3 h, 2.) ether, liq. NH₃, 4 h

With phosphorus pentachloride; hydrogen; sodium amide; trichlorophosphate; platinum(IV) oxide; In ethanol;
DOI:10.1007/BF00760704

Reference yield:

: 91324-25-3
1-Methyl-3-acetylpiperidine

: 91324-40-2
1-Methyl-3-ethynylpiperidine

Guidance literature:: With phosphorus pentachloride; sodium amide; trichlorophosphate; Yield given. Multistep reaction; 1.) 90 deg C, 3 h, 2.) ether, liq. NH₃, 4 h;
DOI:10.1007/BF00760704

Reference yield:

: 91324-40-2
1-Methyl-3-ethynylpiperidine

: 91324-49-1
1-Methyl-3-(3'-hydroxy-3',3'-diphenylpropyn-1'-yl)piperidine methiodide

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) sodamide / 1.) ether, liq. NH₃, 0.5 h, 2.) ether, reflux, 4 h

2: ethanol / 72 h

With sodium amide; In ethanol;
DOI:10.1007/BF00760704