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3-acetyl-1-methylpyridinium iodide is a chemical compound with the molecular formula C8H10NO+I-. It is a derivative of pyridinium, a heterocyclic compound with a nitrogen atom in the ring structure. The compound features a methyl group attached to the first carbon and an acetyl group (a two-carbon acyl group) attached to the third carbon of the pyridine ring. The iodide ion (I-) is present as a counterion, forming a salt with the positively charged pyridinium moiety. 3-acetyl-1-methylpyridinium iodide is often used in organic synthesis and as an intermediate in the preparation of various pharmaceuticals and agrochemicals. Its properties include its role as a strong electrophile and its potential to participate in various chemical reactions, such as nucleophilic substitutions and condensations.

6965-62-4

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6965-62-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 6965-62-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,9,6 and 5 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 6965-62:
(6*6)+(5*9)+(4*6)+(3*5)+(2*6)+(1*2)=134
134 % 10 = 4
So 6965-62-4 is a valid CAS Registry Number.
InChI:InChI=1/C8H10NO/c1-7(10)8-4-3-5-9(2)6-8/h3-6H,1-2H3/q+1

6965-62-4Relevant academic research and scientific papers

Tandem dinucleophilic cyclization of cyclohexane-1,3-diones with pyridinium salts

Kiamehr, Mostafa,Moghaddam, Firouz Matloubi,Mkrtchyan, Satenik,Semeniuchenko, Volodymyr,Supe, Linda,Villinger, Alexander,Langer, Peter,Laroshenko, Viktor O.

supporting information, p. 1119 - 1126 (2013/07/19)

The cyclization of cyclohexane-1,3-diones with various substituted pyridinium salts afforded functionalized 8-oxa-10-aza-tricyclo[7.3.1.0 2,7]trideca-2(7),11-dienes. The reaction proceeds by regioselective attack of the central carbon atom of t

Pyridinium salts - Versatile reagents for the regioselective synthesis of functionalized thiazocino[2,3-b]indoles by tandem dinucleophilic reactions of thiooxindoles

Kiamehr, Mostafa,Gormay, Pavel V.,Villinger, Alexander,Langer, Peter,Iaroshenko, Viktor O.,Moghaddam, Firouz Matloubi,Semeniuchenko, Volodymyr

supporting information, p. 9685 - 9693,9 (2020/08/20)

The reaction of thiooxindoles with various 2- and 3-substituted pyridinium salts afforded a variety of functionalized thiazocinoindoles. The products have been prepared in good to excellent yields by regioselective dinucleophilic C/S-cyclocondensation of

Excellent correlation between substituent constants and pyridinium N-methyl chemical shifts

Huang, Sha,Wong, Jesse C.S.,Leung, Adam K.C.,Chan, Yee Man,Wong, Lili,Fernendez, Myrien R.,Miller, Amanda K.,Wu, Weiming

experimental part, p. 5018 - 5020 (2009/12/01)

Substituents on the pyridinium ring of N-methylpyridinium derivatives, especially those on the 2- or 4-position, have a large effect on the 1H and 13C NMR chemical shifts of the N-methyl group. Reasonable correlations between the chemical shift changes and the resonance substituent constants are observed. The dual substituent parameter approach provides an excellent correlation when a combination of polar and resonance substituent constants is employed.

Substituent effects on formation of cation dimers by weak hydrogen bonds in crystals of carbonyl pyridinium salts of ni(dmit)2

Tomono, Kazuaki,Koyano, Ayako,Morita, Takashi,Miyamura, Kazuo

experimental part, p. 1152 - 1159 (2009/12/25)

Five 1:1 salts of 3-X-1-methylpyridinium (X = benzoyl, acetyl, methoxycarbonyl, carboxy, and aminocarbonyl; abbreviated as Ben, Ace, Met, Car, and Ami, respectively) cations with a [Ni(dmit)2]- anion ([Ben]+[Ni(dmit)2]- (1), Ace] +[Ni(dmit)2]- (2), [Met]+[Ni(dmit) 2]- (3), [Car]+[Ni(dmit)2] - (4), and [Ami]+[Ni(dmit)2]- (5)) have been synthesized and characterized by single-crystal X-ray analysis and conductivity measurements. In the crystals, three cations 1-3 were found to form dimers by weak C-H...O hydrogen bonds, and the arrangements of cations had a strong relation with the electronic effect of the substituents. The cations of 1-3 formed similar centrosymmetrically associated dimers constructed by weak C-H...O hydrogen bonds, whose geometric parameters had a correlation with the electronic effect of the substituents. A cation of 4 also formed centrosymmetrically associated dimer, but it was made by an O-H...O hydrogen bond as usually observed in the case of carboxylic acid. In contrast with other complex salts, cations of 5 formed one-dimensional structure by C-H...O hydrogen bonding. The conductivities of salts 1, 2, 3, 4, and 5 at room temperature were 1.00 × 10-6, 1.10 × 10-6, 2.86 × 10-6, 9.77 × 10-6, and 8.75 × 10 -7Scm-1, respectively.

Substantial formation of hydrates and hemiacetals from pyridinium ketones

Huang, Sha,Miller, Amanda K.,Wu, Weiming

scheme or table, p. 6584 - 6585 (2011/02/24)

Pyridinium ketones have been found to exist as hydrates and hemiacetals in considerable amount in aqueous and alcoholic solutions, respectively. The relative position of the pyridinium positive charge has a large effect on the equilibrium constants. The polar substituent constants, σ,* of the pyridinium group substituted at different positions can be estimated from the hydration constants.

Synthesis of piperidine derivatives by reduction of pyridinium salts

Tang, Zilong,Mayrargue, Joelle,Alami, Mouad

, p. 3367 - 3379 (2008/02/13)

Piperidine derivatives 1a-e and 2a-f have been prepared by the reduction of 3-and 4-substituted pyridinium salts with NaBH4 in moderate to excellent yields. The reactions regioselectively give 1,2,5,6-tetrahydropyridines, and the yields depend greatly upon the nature of substituents on the phenyl ring and on the nitrogen atom, the nature and the position of the substituents on the pyridyl ring, and the chain length between the aryloxy and the pyridyl groups. Copyright Taylor & Francis Group, LLC.

Kinetics of Quaternization of trans-4-(p- or m-Substituted styryl)pyridines with Methyl Iodide

Ananthakrishnanadar, P.,Rajasekaran, K.

, p. 324 - 325 (2007/10/02)

Second order rate constants have been measured for the reaction of several trans-4-(p- or m-substituted styryl)pyridines with methyl iodide in nitrobenzene at 30 deg C, 35 deg C, and 40 deg C.Arrhenius parameters as well as enthalpies and entropies of act

COVALENT ADDUCTS FROM 1,3-DISUBSTITUTED PYRIDINIUM SALTS AND PIPERIDINE

Moracci, F. Micheletti,Rienzo, B. Di,Tortorella, S.,Liberatore, F.

, p. 785 - 789 (2007/10/02)

Covalent adducts 3a-f have been isolated from the reaction between piperidine and pyridinium salts 1a-f. 3a-f are stable both in the solid state and in apolar solvents, whereas their fast dissociation back to piperidine and pyridinium ions occurs in aqueous solution.The latter, in the alkaline environment produced by the amine, yields the correspondent pseudobases, which are key intermediates of the subsequent reactions.For instance, the pseudobases from 1a,b can undergo either a ring-opening reaction or a redox process with the corresponding pyridinium cations.

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