1-(2-(Benzyloxy)biphenyl-3-yl)ethanone

Base Information

Chemical Name:1-(2-(Benzyloxy)biphenyl-3-yl)ethanone
CAS No.:913721-75-2
Molecular Formula:C21H18O2
Molecular Weight:302.373
Hs Code.:
DSSTox Substance ID:DTXSID60475477
Wikidata:Q82306037

Synonyms:1-(2-(Benzyloxy)biphenyl-3-yl)ethanone;913721-75-2;AGN-PC-00JG5B;SCHEMBL1639034;DTXSID60475477;VONJAWORXGYVEQ-UHFFFAOYSA-N

Suppliers and Price of 1-(2-(Benzyloxy)biphenyl-3-yl)ethanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 1 raw suppliers

Chemical Property of 1-(2-(Benzyloxy)biphenyl-3-yl)ethanone

Chemical Property:

XLogP3:4.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:5
Exact Mass:302.130679813
Heavy Atom Count:23
Complexity:366

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(=O)C1=CC=CC(=C1OCC2=CC=CC=C2)C3=CC=CC=C3

Technology Process of 1-(2-(Benzyloxy)biphenyl-3-yl)ethanone

There total 3 articles about 1-(2-(Benzyloxy)biphenyl-3-yl)ethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

: 21424-82-8
1-(2-hydroxy-[1,1'-biphenyl]-3-yl)ethanone

: 100-39-0
benzyl bromide

: 913721-75-2
2-benzyloxy-3-phenylacetophenone

Guidance literature:: With sodium hydroxide; tetrabutylammomium bromide; In dichloromethane; at 20 ℃; for 24h;
DOI:10.1021/jm060358r

Reference yield:

: 3271-80-5
2-acetoxybiphenyl

: 913721-75-2
2-benzyloxy-3-phenylacetophenone

Guidance literature:: Multi-step reaction with 2 steps

1: 74.5 percent / aluminum chloride / 1,2-dichloro-benzene / 24 h / 100 °C

2: 63 percent / tetrabutylammonium bromide; aq. NaOH / CH₂Cl₂ / 24 h / 20 °C

With sodium hydroxide; aluminium trichloride; tetrabutylammomium bromide; In dichloromethane; 1,2-dichloro-benzene; 1: Fries rearrangement;
DOI:10.1021/jm060358r

Reference yield:

: 90-43-7,287950-96-3
2-Phenylphenol

: 913721-75-2
2-benzyloxy-3-phenylacetophenone

Guidance literature:: Multi-step reaction with 3 steps

1: 100 percent / pyridine / CH₂Cl₂ / 3 h

2: 74.5 percent / aluminum chloride / 1,2-dichloro-benzene / 24 h / 100 °C

3: 63 percent / tetrabutylammonium bromide; aq. NaOH / CH₂Cl₂ / 24 h / 20 °C

With pyridine; sodium hydroxide; aluminium trichloride; tetrabutylammomium bromide; In dichloromethane; 1,2-dichloro-benzene; 2: Fries rearrangement;
DOI:10.1021/jm060358r