cussonoside A

Base Information

• Chemical Name: cussonoside A
• CAS No.: 57539-70-5
• Molecular Formula: C48H78 O18
• Molecular Weight: 943.137
• Mol file: 57539-70-5.mol

Synonyms:CussonosideA; HN saponin H; Hederagenin 28-O-a-L-rhamnopyranosyl-(1®4)-b-D-glucopyranosyl-(1®6)-b-D-glucopyranosyl ester; Kalopanaxsaponin G;Kalopanaxsaponin G (C48); Pulsatiloside C

Chemical Property of cussonoside A

Chemical Property:

• Boiling Point: 1001.7°Cat760mmHg
• Flash Point: 283.9°C
• PSA: 294.98000
• Density: 1.41g/cm³
• LogP: 0.14050

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of cussonoside A

There total 3 articles about cussonoside A which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

HN-saponin P (14216-03-6,27013-76-9) → prosapogenin (17184-21-3) + hederagenin 28-O-β-D-glucopyranosyl-(1->6)-O-β-D-glucopyranosyl ester (99624-66-5) + 3β,23-dihydroxyolean-12-en-28-oic acid O-α-L-rhamnopyranosyl-(1->4)-O-β-D-glucopyranosyl-(1->6)-β-D-glucopyranosyl ester (57539-70-5) + alpha-Hederin (27013-91-8)

Guidance literature:

With sulfuric acid; In ethanol; for 2h; Further byproducts given; Heating;

DOI:10.1248/cpb.33.3473

Reference yield:

nipponoside A → 3β,23-dihydroxyolean-12-en-28-oic acid O-α-L-rhamnopyranosyl-(1->4)-O-β-D-glucopyranosyl-(1->6)-β-D-glucopyranosyl ester (57539-70-5)

Guidance literature:

With sodium tetrahydroborate; In methanol; for 0.333333h; Ambient temperature;

DOI:10.1021/np9804334

Reference yield:

hederagenin-3-O-α-L-rhamnopyranosyl-(1->2)-O-α-L-arabinopyranosyl-28-O-α-L-rhamnopyranosyl-(1->4)-O-6-O-acetyl-β-D-glucopyranosyl-(1->6)-O-β-D-glucopyranosyl ester (97240-03-4) → 3β,23-dihydroxyolean-12-en-28-oic acid O-α-L-rhamnopyranosyl-(1->4)-O-β-D-glucopyranosyl-(1->6)-β-D-glucopyranosyl ester (57539-70-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 14 mg / 0.1 N aq. KOH / 20 h / Ambient temperature

2: 155 mg / 0.05 N H₂SO₄ / ethanol / 2 h / Heating

With potassium hydroxide; sulfuric acid; In ethanol;

DOI:10.1248/cpb.33.3473

upstream raw materials:

HN-saponin P

hederagenin-3-O-α-L-rhamnopyranosyl-(1->2)-O-α-L-arabinopyranosyl-28-O-α-L-rhamnopyranosyl-(1->4)-O-6-O-acetyl-β-D-glucopyranosyl-(1->6)-O-β-D-glucopyranosyl ester

Refernces

• 1、 Kizu,Hirabayashi,Suzuki,Tomimori. "Studies on the constituents of Hedera rhombea Bean. IV. On the hederagenin glycosides". . p. 3473 - 3478. Retrieved 2007/10/02.