N-[2-(2,6-DiMethylphenoxy)-1-Methylethyl]acetaMide

Base Information

Chemical Name:N-[2-(2,6-DiMethylphenoxy)-1-Methylethyl]acetaMide
CAS No.:91452-27-6
Molecular Formula:C13H19NO2
Molecular Weight:221.299
Hs Code.:
Mol file:91452-27-6.mol

Synonyms:Acetamide,N-[2-(2,6-dimethylphenoxy)-1-methylethyl];Mexiletine acetate;N-[2-(2,6-dimethylphenoxy)-1-methylethyl]-acetamide;

Suppliers and Price of N-[2-(2,6-DiMethylphenoxy)-1-Methylethyl]acetaMide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N-[2-(2,6-Dimethylphenoxy)-1-methylethyl]acetamide
10g
$ 1190.00

Total 4 raw suppliers

Chemical Property of N-[2-(2,6-DiMethylphenoxy)-1-Methylethyl]acetaMide

Chemical Property:

Melting Point:85-86°C
PSA：41.82000
LogP:3.04710
Storage Temp.:-20°C Freezer
Solubility.:Chloroform (Slightly), Methanol (Slightly)

Purity/Quality:

99% ^*data from raw suppliers

N-[2-(2,6-Dimethylphenoxy)-1-methylethyl]acetamide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses N-[2-(2,6-dimethylphenoxy)-1-methylethyl]acetamide is an impurity of Mexiletine (M340800), an antiarrhythmic agent.

Technology Process of N-[2-(2,6-DiMethylphenoxy)-1-Methylethyl]acetaMide

There total 2 articles about N-[2-(2,6-DiMethylphenoxy)-1-Methylethyl]acetaMide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 5370-01-4
(rac)-mexiletine hydrochloride

: 75-36-5
acetyl chloride

: 91452-27-6
N-(1-(2,6-dimethylphenoxy)propan-2-yl)acetamide

Guidance literature:: With sodium hydroxide; In water; ethyl acetate;

Reference yield:

: 31828-71-4
RS-mexiletine

: 91452-27-6
N-(1-(2,6-dimethylphenoxy)propan-2-yl)acetamide

Guidance literature:: Multi-step reaction with 2 steps

1: hydrogenchloride / dichloromethane; diethyl ether

2: triethylamine / dichloromethane / 15 h / 21 °C

With hydrogenchloride; triethylamine; In diethyl ether; dichloromethane;
DOI:10.1021/acs.jmedchem.0c01545