(5-Fluoro-2-{[4-(propan-2-yl)phenyl]sulfanyl}phenyl)methanol

Base Information

Chemical Name:(5-Fluoro-2-{[4-(propan-2-yl)phenyl]sulfanyl}phenyl)methanol
CAS No.:91527-97-8
Molecular Formula:C16H17FOS
Molecular Weight:276.375
Hs Code.:
DSSTox Substance ID:DTXSID70523211
Wikidata:Q82389171

Synonyms:91527-97-8;DTXSID70523211;(5-Fluoro-2-{[4-(propan-2-yl)phenyl]sulfanyl}phenyl)methanol;AKOS013126086

Suppliers and Price of (5-Fluoro-2-{[4-(propan-2-yl)phenyl]sulfanyl}phenyl)methanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (5-Fluoro-2-{[4-(propan-2-yl)phenyl]sulfanyl}phenyl)methanol

Chemical Property:

XLogP3:4.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:276.09841450
Heavy Atom Count:19
Complexity:264

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)C1=CC=C(C=C1)SC2=C(C=C(C=C2)F)CO

Technology Process of (5-Fluoro-2-{[4-(propan-2-yl)phenyl]sulfanyl}phenyl)methanol

There total 3 articles about (5-Fluoro-2-{[4-(propan-2-yl)phenyl]sulfanyl}phenyl)methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 91527-94-5
5-fluoro-2-(4-isopropylphenylthio)benzoic acid

: 91527-97-8
5-fluoro-2-(4-isopropylphenylthio)benzyl alcohol

Guidance literature:: With sodium bis(2-methoxyethoxy)aluminium dihydride; In toluene; benzene; at 40 ℃; for 3h;
DOI:10.1135/cccc19840086

Reference yield:

: 4946-14-9
4-mercapto-cumene

: 91527-97-8
5-fluoro-2-(4-isopropylphenylthio)benzyl alcohol

Guidance literature:: Multi-step reaction with 2 steps

1: 96 percent / KOH, Cu / H₂O / 1. 60 deg C, 15 min 2. reflux, 6h

2: 86 percent / sodium dihydrobis(2-methoxyetoxy)aluminate / benzene; toluene / 3 h / 40 °C

With potassium hydroxide; copper; sodium bis(2-methoxyethoxy)aluminium dihydride; In water; toluene; benzene;
DOI:10.1135/cccc19840086

Reference yield:

: 52548-63-7
5-fluoro-2-iodobenzoic acid

: 91527-97-8
5-fluoro-2-(4-isopropylphenylthio)benzyl alcohol

Guidance literature:: Multi-step reaction with 2 steps

1: 96 percent / KOH, Cu / H₂O / 1. 60 deg C, 15 min 2. reflux, 6h

2: 86 percent / sodium dihydrobis(2-methoxyetoxy)aluminate / benzene; toluene / 3 h / 40 °C

With potassium hydroxide; copper; sodium bis(2-methoxyethoxy)aluminium dihydride; In water; toluene; benzene;
DOI:10.1135/cccc19840086