2-Benzyloxybenzyl alcohol

Base Information

• Chemical Name: 2-Benzyloxybenzyl alcohol
• CAS No.: 3381-87-1
• Molecular Formula: C14H14O2
• Molecular Weight: 214.264
• Hs Code.: 2909499000
• European Community (EC) Number: 630-896-4
• DSSTox Substance ID: DTXSID50187471
• Nikkaji Number: J122.291K
• Wikidata: Q83059175
• Mol file: 3381-87-1.mol

Synonyms:2-Benzyloxybenzyl alcohol;3381-87-1;(2-(Benzyloxy)phenyl)methanol;Benzyl ether of saligenin;(2-phenylmethoxyphenyl)methanol;[2-(Benzyloxy)phenyl]methanol;Benzenemethanol, 2-(phenylmethoxy)-;BENZYL ALCOHOL, o-(BENZYLOXY)-;2-(Phenylmethoxy)benzenemethanol;BRN 2212681;MFCD01664428;Benzenemethanol, 2-(phenylmethoxy)- (9CI);2-(benzyloxy)benzyl alcohol;2-BENZYLOXYBENZYLALCOHOL;MLS003675150;SCHEMBL692555;DTXSID50187471;[2-(Benzyloxy)phenyl]methanol #;AKOS000125307;AS-44397;LS-42721;SMR001490975;[2-(Benzyloxy)phenyl]methanol, AldrichCPR;B2943;CS-0196084;EN300-139256

Chemical Property of 2-Benzyloxybenzyl alcohol

Chemical Property:

• Vapor Pressure: 8.32E-06mmHg at 25°C
• Melting Point: 36.5-37.5 °C
• Boiling Point: 359.9°Cat760mmHg
• PKA: 14.40±0.10(Predicted)
• Flash Point: 162.1°C
• PSA: 29.46000
• Density: 1.139g/cm³
• LogP: 2.75790
• XLogP3: 1.7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• Exact Mass: 214.099379685
• Heavy Atom Count: 16
• Complexity: 187

Purity/Quality:

98% ^*data from raw suppliers

2-Benzyloxybenzyl Alcohol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)COC2=CC=CC=C2CO

Technology Process of 2-Benzyloxybenzyl alcohol

There total 20 articles about 2-Benzyloxybenzyl alcohol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.9%

2-(phenylmethoxy)benzaldehyde (5896-17-3) → 2-benzyloxybenzyl alcohol (3381-87-1)

Guidance literature:

With sodium tetrahydroborate; In methanol; at 20 ℃; for 0.5h;

DOI:10.1021/jm051060o

Reference yield: 94.0%

salicylic alcohol (90-01-7) + benzyl bromide (100-39-0) → 2-benzyloxybenzyl alcohol (3381-87-1)

Guidance literature:

With potassium carbonate; In acetone; for 4h; Heating;

DOI:10.1016/j.bmc.2005.10.051

Reference yield: 92.0%

C22H22O3 → 2-benzyloxybenzyl alcohol (3381-87-1)

Guidance literature:

With carbon tetrabromide; In methanol; for 4h; Heating;

DOI:10.1246/cl.2000.566

upstream raw materials:

2-(phenylmethoxy)benzaldehyde

salicylic alcohol

benzyl bromide

2-methyl-benzyl alcohol

Downstream raw materials:

5-C-(o-Benzyloxybenzyl)-2,4-dihydroxyacetophenone

3-C-(o-Benzyloxy)-2,4-dihydroxyacetophenone

5-C-(o-Benzyloxybenzyl)-4,6-dihydroxy-2-methoxyacetophenone

3-C-(o-Benzyloxybenzyl)-4,6-dihydroxy-2-methoxyacetophenone