Perfluoro-2-butyltetrahydrofuran

Base Information

• Chemical Name: Perfluoro-2-butyltetrahydrofuran
• CAS No.: 335-36-4
• Deprecated CAS: 11072-16-5,12627-87-1
• Molecular Formula: C8F16O
• Molecular Weight: 416.062
• Hs Code.: 29321900
• European Community (EC) Number: 206-389-5,254-933-5
• UNII: MSL8VN7XHA
• DSSTox Substance ID: DTXSID60871632
• Nikkaji Number: J95.342C
• Wikipedia: FC-75
• Wikidata: Q5424695
• Mol file: 335-36-4.mol

Synonyms:FC 75;FC-77;Fluorinert;fluorocarbon 75;fluorocarbon 77

Chemical Property of Perfluoro-2-butyltetrahydrofuran

Chemical Property:

• Appearance/Colour: clear colourless liquid
• Melting Point: -88 °C
• Refractive Index: n20/D 1.296
• Boiling Point: 96.6 °C at 760 mmHg
• Flash Point: 17.6 °C
• PSA: 9.23000
• Density: 1.78 g/cm³
• LogP: 5.01400
• Water Solubility.: Insoluble
• XLogP3: 5.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 17
• Rotatable Bond Count: 3
• Exact Mass: 415.9693652
• Heavy Atom Count: 25
• Complexity: 545

Purity/Quality:

98%,99%, ^*data from raw suppliers

Perfluoro(2-butyltetrahydrofuran) (so called) ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 53
• Safety Statements: 61

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Other Classes -> Halogenated Ethers
• Canonical SMILES: C1(C(C(OC1(C(C(C(C(F)(F)F)(F)F)(F)F)(F)F)F)(F)F)(F)F)(F)F
• Uses: Perfluoro(2-butyltetrahydrofuran) is used in production of Fluorine-containing polymers.

Technology Process of Perfluoro-2-butyltetrahydrofuran

There total 11 articles about Perfluoro-2-butyltetrahydrofuran which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 37.8%

4-(perfluoro-n-butyl)-n-butanoyl chloride (124778-16-1) → perfluoroheptane (335-57-9) + perfluorooctanoyl fluoride (335-66-0) + 2,2,3,3,4,4,5-heptafluoro-5-nonafluorobutyl-tetrahydro-furan (335-36-4,11072-16-5)

Guidance literature:

In hydrogen fluoride; at 5 ℃; for 26h; Product distribution; Mechanism; electrochemical fluorination, various conditions, comparison with industrial procedures;

DOI:10.1016/S0022-1139(00)84147-0

Reference yield: 27.9%

n-octanoic acid chloride (111-64-8) → perfluoro-2-butyl-tetrahydrofuran (335-35-3) + perfluoroheptane (335-57-9) + perfluorooctanoyl fluoride (335-66-0) + 2,2,3,3,4,4,5-heptafluoro-5-nonafluorobutyl-tetrahydro-furan (335-36-4,11072-16-5)

Guidance literature:

In hydrogen fluoride; at 5 ℃; for 77h; electrochemical fluorination;

DOI:10.1016/S0022-1139(00)84147-0

Reference yield: 14.9%

4-(perfluoro-n-butyl)-n-butanoyl chloride (124778-16-1) → perfluoroheptane (335-57-9) + perfluorooctanoyl fluoride (335-66-0) + 2,2,3,3,4,4,5-heptafluoro-5-nonafluorobutyl-tetrahydro-furan (335-36-4,11072-16-5)

Guidance literature:

In hydrogen fluoride; at 5 ℃; for 27h; electrochemical fluorination;

DOI:10.1016/S0022-1139(00)84147-0

upstream raw materials:

Octanoic acid

2-propyltetrahydropyran

2-(2'-Propyl)tetrahydropyran

octanoic acid fluoride

Refernces

• 1、 Prokop, H.W.,Zhou, H-J,Xu, S-Q,Wu, C-H,Liu, C. C.. "ANALYSIS OF THE PRODUCTS FROM THE ELECTROCHEMICAL FLUORINATION OF OCTANOYL CHLORIDE". . p. 277 - 290. Retrieved 2007/10/02.
• 2、 Abe, Takashi,Hayashi, Eiji,Baba, Hajime,Kodaira, Kazuo,Nagase, Shunji. "FLUORINATION OF 2-ALKYL-SUBSTITUTED OXIRANES. THE SYNTHESIS AND PURIFICATION OF PERFLUORO(2-ALKYL-SUBSTITUTED OXANE)S". . p. 353 - 380. Retrieved 2007/10/02.