Benzoic acid, 4-[3-[5-chloro-1-(diphenylmethyl)-2-[2-[[[[2-(hydroxymethyl)phenyl]methyl ]sulfonyl]amino]ethyl]-1H-indol-3-yl]propyl]-, methyl ester

Base Information

Chemical Name:Benzoic acid, 4-[3-[5-chloro-1-(diphenylmethyl)-2-[2-[[[[2-(hydroxymethyl)phenyl]methyl ]sulfonyl]amino]ethyl]-1H-indol-3-yl]propyl]-, methyl ester
CAS No.:916136-49-7
Molecular Formula:C42H41ClN2O5S
Molecular Weight:721.317
Hs Code.:

Benzoic acid,
4-[3-[5-chloro-1-(diphenylmethyl)-2-[2-[[[[2-(hydroxymethyl)phenyl]methyl
]sulfonyl]amino]ethyl]-1H-indol-3-yl]propyl]-, methyl ester

Synonyms:

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Benzoic acid, 4-[3-[5-chloro-1-(diphenylmethyl)-2-[2-[[[[2-(hydroxymethyl)phenyl]methyl ]sulfonyl]amino]ethyl]-1H-indol-3-yl]propyl]-, methyl ester

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Technology Process of Benzoic acid, 4-[3-[5-chloro-1-(diphenylmethyl)-2-[2-[[[[2-(hydroxymethyl)phenyl]methyl ]sulfonyl]amino]ethyl]-1H-indol-3-yl]propyl]-, methyl ester

There total 2 articles about Benzoic acid, 4-[3-[5-chloro-1-(diphenylmethyl)-2-[2-[[[[2-(hydroxymethyl)phenyl]methyl ]sulfonyl]amino]ethyl]-1H-indol-3-yl]propyl]-, methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 41.0%

: 916136-83-9
methyl 4-{3-[5-chloro-1-(diphenylmethyl)-2-(2-{[(2-formylbenzyl)-sulfonyl]amino}ethyl)-1H-indol-3-yl]propyl}benzoate

: 109-89-7
diethylamine

: 916136-49-7
methyl 4-(3-{5-chloro-1-(diphenylmethyl)-2-[2-({[2-(hydroxymethyl)benzyl]sulfonyl}amino)ethyl]-1H-indol-3-yl}propyl)benzoate

: 916136-47-5
methyl 4-{3-[5-chloro-2-{2-[({2-[(diethylamino)methyl]benzyl}sulfonyl)amino]ethyl}-1-(diphenylmethyl)-1H-indol-3-yl]propyl}benzoate

Guidance literature:: With sodium tris(acetoxy)borohydride; In 1,2-dichloro-ethane; at 0 - 20 ℃;
DOI:10.1021/jm8009876

Reference yield: 41.0%

: 916136-49-7
methyl 4-(3-{5-chloro-1-(diphenylmethyl)-2-[2-({[2-(hydroxymethyl)benzyl]sulfonyl}amino)ethyl]-1H-indol-3-yl}propyl)benzoate

: 916136-47-5
methyl 4-{3-[5-chloro-2-{2-[({2-[(diethylamino)methyl]benzyl}sulfonyl)amino]ethyl}-1-(diphenylmethyl)-1H-indol-3-yl]propyl}benzoate

Guidance literature:

Reference yield: 61.0%

: 916136-49-7
methyl 4-(3-{5-chloro-1-(diphenylmethyl)-2-[2-({[2-(hydroxymethyl)benzyl]sulfonyl}amino)ethyl]-1H-indol-3-yl}propyl)benzoate

: 4-(3-{5-chloro-1-(diphenylmethyl)-2-[2-({[2-(hydroxymethyl)benzyl]sulfonyl}amino)ethyl]-1H-indol-3-yl}propyl)benzoic acid

Guidance literature:: methyl 4-(3-{5-chloro-1-(diphenylmethyl)-2-[2-({[2-(hydroxymethyl)benzyl]sulfonyl}amino)ethyl]-1H-indol-3-yl}propyl)benzoate; With sodium hydroxide; In tetrahydrofuran; methanol; water; at 20 ℃;

With hydrogenchloride; In tetrahydrofuran; methanol; water; at 20 ℃; pH=Ca. 3;
DOI:10.1021/jm8009876