methyl 2-[3-(1-pyridin-3-ylethenyl)-1H-indol-2-yl]acetate

Base Information

Chemical Name:methyl 2-[3-(1-pyridin-3-ylethenyl)-1H-indol-2-yl]acetate
CAS No.:91653-14-4
Molecular Formula:C18H16N2O2
Molecular Weight:292.337
Hs Code.:
DSSTox Substance ID:DTXSID70550148
Nikkaji Number:J1.642.714D
Wikidata:Q82429371

Synonyms:91653-14-4;methyl 2-[3-(1-pyridin-3-ylethenyl)-1H-indol-2-yl]acetate;SCHEMBL9678059;DTXSID70550148;YUNTXRAZEACNBV-UHFFFAOYSA-N;1-[2-(Carbomethoxymethyl)-3-indolyl]-1-(3-pyridyl) ethene;Methyl {3-[1-(pyridin-3-yl)ethenyl]-1H-indol-2-yl}acetate;2-[3-(1-pyridin-3-yl-vinyl)-1H-indol-2-yl]-acetic acid methyl ester

Suppliers and Price of methyl 2-[3-(1-pyridin-3-ylethenyl)-1H-indol-2-yl]acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of methyl 2-[3-(1-pyridin-3-ylethenyl)-1H-indol-2-yl]acetate

Chemical Property:

XLogP3:3.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:292.121177757
Heavy Atom Count:22
Complexity:423

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)CC1=C(C2=CC=CC=C2N1)C(=C)C3=CN=CC=C3

Technology Process of methyl 2-[3-(1-pyridin-3-ylethenyl)-1H-indol-2-yl]acetate

There total 1 articles about methyl 2-[3-(1-pyridin-3-ylethenyl)-1H-indol-2-yl]acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 32588-36-6
indolylacetic acid

: 91653-14-4
1-<2-(carbomethoxymethyl)-3-indolyl>-1-(3-pyridyl)ethene

Guidance literature:: Multi-step reaction with 2 steps

2: 82 percent / HBr / methanol

With hydrogen bromide; In methanol;
DOI:10.1016/S0040-4039(01)81172-2

Reference yield: 92.0%

: 91653-14-4
1-<2-(carbomethoxymethyl)-3-indolyl>-1-(3-pyridyl)ethene

: 100-11-8
1-bromomethyl-4-nitro-benzene

: 108320-73-6
3-[1-(2-Methoxycarbonylmethyl-1H-indol-3-yl)-vinyl]-1-(4-nitro-benzyl)-pyridinium; bromide

Guidance literature:: In acetone; for 24h;
DOI:10.1021/jm00390a014

Reference yield:

: 141282-26-0
2-[2-(1,3-dioxoisoindolin-2-yl)ethoxy]ethyl 4-methylbenzenesulfonate

: 91653-14-4
1-<2-(carbomethoxymethyl)-3-indolyl>-1-(3-pyridyl)ethene

: 1618136-53-0
C₃₀H₂₆N₃O₅⁽¹⁺⁾*C₇H₇O₃S^(1-)

Guidance literature:: 2-[2-(1,3-dioxoisoindolin-2-yl)ethoxy]ethyl 4-methylbenzenesulfonate; 1-<2-(carbomethoxymethyl)-3-indolyl>-1-(3-pyridyl)ethene; In N,N-dimethyl-formamide; at 110 ℃; for 15h;

With sodium methylate; In methanol; N,N-dimethyl-formamide; at 20 ℃; for 1h;

With 3-ethoxycarbonyl-1-methylpyridinium chloride; In methanol; N,N-dimethyl-formamide; at 20 ℃; for 5h;
DOI:10.1016/j.ejmech.2014.05.032