3,4-dihydroxyphenylglycine

Base Information

• Chemical Name: 3,4-dihydroxyphenylglycine
• CAS No.: 16534-84-2
• Molecular Formula: C₈H₉NO₄
• Molecular Weight: 183.164
• Mol file: 16534-84-2.mol

Synonyms:Glycine,2-(3,4-dihydroxyphenyl)- (6CI); Glycine, a-(3,4-dihydroxyphenyl)- (7CI,8CI); (?à)-2-Amino-2-(3,4-dihydroxyphenyl)aceticacid; 2-(3,4-Dihydroxyphenyl)glycine; 3,4-Dihydroxyphenylglycine; a-(3,4-Dihydroxyphenyl)glycine; a-Amino-3,4-dihydroxyphenylaceticacid

Chemical Property of 3,4-dihydroxyphenylglycine

Chemical Property:

• Vapor Pressure: 1.39E-08mmHg at 25°C
• Boiling Point: 441.8°C at 760 mmHg
• Flash Point: 221°C
• PSA: 89.79000
• Density: 1.55g/cm³
• LogP: 0.66730

Purity/Quality:

98%Min ^*data from raw suppliers

3,4-DIHYDROXYPHENYLGLYCINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3,4-dihydroxyphenylglycine

There total 5 articles about 3,4-dihydroxyphenylglycine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

D-α-amino-m,p-dimethoxyphenylacetic acid (91819-11-3) → DL-2-(3,4-Dihydroxyphenyl)glycin (138-62-5,16534-84-2)

Guidance literature:

With hydrogen bromide; for 3h; Heating;

Reference yield:

amino-(4-hydroxy-3-methoxy-phenyl)-acetic acid (56246-88-9) → DL-2-(3,4-Dihydroxyphenyl)glycin (138-62-5,16534-84-2)

Guidance literature:

With hydrogen iodide;

Reference yield:

D-4-hydroxyphenylglycine (22818-40-2) → D-(-)-3,4-dihydroxyphenylglycine (56144-53-7,16534-84-2)

Guidance literature:

With dihydroxyfumaric acid; acetate buffer; oxygen; horse radish peroxidase; at 0 ℃; for 3h;

DOI:10.1021/ja00410a067

upstream raw materials:

amino-(4-hydroxy-3-methoxy-phenyl)-acetic acid

D-α-amino-m,p-dimethoxyphenylacetic acid

vanillin

D-4-hydroxyphenylglycine

Refernces

• 1、 Klibanov, Alexander M.,Berman, Zina,Alberti, Barbara N.. "Preparative Hydroxylation of Aromatic Compounds Catalyzed by Peroxidase". . p. 6263 - 6264. Retrieved 2007/10/02.