Guvacine

Base Information

Chemical Name:Guvacine
CAS No.:498-96-4
Molecular Formula:C6H9NO2
Molecular Weight:127.143
Hs Code.:
UNII:41538P325K
DSSTox Substance ID:DTXSID50871702
Nikkaji Number:J11.591F
Wikipedia:Guvacine
Wikidata:Q15322708
Metabolomics Workbench ID:67456
ChEMBL ID:CHEMBL76768
Mol file:498-96-4.mol

Synonyms:guvacine;guvacine hydrobromide;guvacine hydrochloride

Suppliers and Price of Guvacine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Guvacine hydrochloride
100mg
$ 446.00

J&W Pharmlab
1,2,5,6-Tetrahydro-pyridine-3-carboxylicacid 97%
5g
$ 598.00

J&W Pharmlab
1,2,5,6-Tetrahydro-pyridine-3-carboxylicacid 97%
500mg
$ 146.00

J&W Pharmlab
1,2,5,6-Tetrahydro-pyridine-3-carboxylicacid 97%
100mg
$ 109.00

J&W Pharmlab
1,2,5,6-Tetrahydro-pyridine-3-carboxylicacid 97%
50mg
$ 98.00

J&W Pharmlab
1,2,5,6-Tetrahydro-pyridine-3-carboxylicacid 97%
1g
$ 185.00

DC Chemicals
Guvacine hydrochloride >98%,StandardReferencesGrade
20 mg
$ 280.00

Crysdot
1,2,5,6-Tetrahydropyridine-3-carboxylicacid 95+%
1g
$ 549.00

ChemScene
Guvacine
1mg
$ 150.00

Chemenu
1,2,5,6-Tetrahydro-pyridine-3-carboxylicacid 95%
1g
$ 513.00

Total 54 raw suppliers

Chemical Property of Guvacine

Chemical Property:

Vapor Pressure:0.000983mmHg at 25°C
Melting Point:295°C (rough estimate)
Refractive Index:1.4645 (estimate)
Boiling Point:280.8°Cat760mmHg
PKA:3.61±0.20(Predicted)
Flash Point:123.6°C
PSA：49.33000
Density:1.199g/cm³
LogP:1.12150
Storage Temp.:Store at RT
Solubility.:H2O: soluble
XLogP3:-2.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:127.063328530
Heavy Atom Count:9
Complexity:151

Purity/Quality:

HPLC≥98% ^*data from raw suppliers

Guvacine hydrochloride ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CNCC(=C1)C(=O)O
Uses Guvacine Hydrochloride is a GABA uptake inhibitor (hGABA T-1, rGABA T-2, hGABA T-3 and hBGT-1) (1,2,3). Gamma-Aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain (4). Guvacine Hydrochloride may be useful for treating neuropsychiatric disorders.

Technology Process of Guvacine

There total 17 articles about Guvacine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%