2-Pyrrolidinecarbonyl chloride, 1-(trifluoroacetyl)-

Base Information

• Chemical Name: 2-Pyrrolidinecarbonyl chloride, 1-(trifluoroacetyl)-
• CAS No.: 92076-92-1
• Molecular Formula: C7H7ClF3NO2
• Molecular Weight: 229.586
• DSSTox Substance ID: DTXSID50392048

Synonyms:2-Pyrrolidinecarbonyl chloride, 1-(trifluoroacetyl)-;92076-92-1;1-(2,2,2-trifluoroacetyl)pyrrolidine-2-carbonyl chloride;1-(trifluoroacetyl)pyrrolidine-2-carbonyl chloride;SCHEMBL2036130;DTXSID50392048;1-(Trifluoroacetyl)prolyl chloride;MFCD05618115;AKOS015948572;FT-0639332;PHOSPHORICACIDTRIS(1,3-DICHLORO-2-PROPYL)ESTER

Chemical Property of 2-Pyrrolidinecarbonyl chloride, 1-(trifluoroacetyl)-

Chemical Property:

• PSA: 37.38000
• LogP: 1.24300
• XLogP3: 1.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 1
• Exact Mass: 229.0117406
• Heavy Atom Count: 14
• Complexity: 266

Purity/Quality:

98% ^*data from raw suppliers

1-(2,2,2-Trifluoroacetyl)pyrrolidine-2-carbonyl chloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CC(N(C1)C(=O)C(F)(F)F)C(=O)Cl

Technology Process of 2-Pyrrolidinecarbonyl chloride, 1-(trifluoroacetyl)-

There total 2 articles about 2-Pyrrolidinecarbonyl chloride, 1-(trifluoroacetyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-trifluoroacetyl-DL-proline (92076-93-2) → (-)-N-(trifluoroacetyl)prolyl chloride (92076-92-1)

Guidance literature:

With Chloro-oxo-acetic acid; In pyridine; benzene; for 0.25h; Heating;

DOI:10.1021/jo00196a001

Reference yield:

→ (-)-N-(trifluoroacetyl)prolyl chloride (92076-92-1)

Guidance literature:

Reference yield: 98.0%

(S)-1-phenyl-ethylamine (2627-86-3) + (-)-N-(trifluoroacetyl)prolyl chloride (92076-92-1) → N-trifluoroacetyl-dl-proline S-α-phenylethylamide

Guidance literature:

With potassium carbonate; In dichloromethane; water; at 20 ℃; for 0.5h;

DOI:10.1007/BF00957527

upstream raw materials:

N-trifluoroacetyl-DL-proline

Downstream raw materials:

2,2,2-Trifluoro-1-[2-(1-hydroxy-cyclohexyl)-pyrrolidin-1-yl]-ethanone

-3,4-dimethoxybenzene

1-(2-benzoylpyrrolidin-1-yl)-2,2,2-trifluoroethan-1-one

2,2,2-trifluoro-1-pyrrolidin-1-ylethanone

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 92076-92-1 2-Pyrrolidinecarbonyl chloride, 1-(trifluoroacetyl)-

Send

Send

Metric Ton KG G Pound L ML

Send

Send