Cryptophycin 21

Base Information

Chemical Name:Cryptophycin 21
CAS No.:168569-15-1
Molecular Formula:C₃₄H₄₁ClN₂O₈
Molecular Weight:641.161
Hs Code.:
DSSTox Substance ID:DTXSID401046568
Nikkaji Number:J833.403J
Wikidata:Q105100122
Metabolomics Workbench ID:139818
ChEMBL ID:CHEMBL502895

Synonyms:Cryptophycin 21;Cryptophycin-21;CHEMBL502895;SCHEMBL10048476;ATKRDMWWPRZLSY-BJJCRNJMSA-N;DTXSID401046568;168569-15-1

Suppliers and Price of Cryptophycin 21

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Cryptophycin 21

Chemical Property:

XLogP3:5.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:8
Exact Mass:640.2551440
Heavy Atom Count:45
Complexity:1050

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)CC1C(=O)OC(CC=CC(=O)NC(C(=O)NCCC(=O)O1)CC2=CC(=C(C=C2)OC)Cl)C(C)C3C(O3)C4=CC=CC=C4
Isomeric SMILES:C[C@@H]([C@@H]1C/C=C/C(=O)N[C@@H](C(=O)NCCC(=O)O[C@H](C(=O)O1)CC(C)C)CC2=CC(=C(C=C2)OC)Cl)[C@@H]3[C@H](O3)C4=CC=CC=C4

Technology Process of Cryptophycin 21

There total 5 articles about Cryptophycin 21 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 6.8%

: 171674-92-3
cryptophycin-31

: 168569-15-1
cryptophycin-27

Guidance literature:: With lithium chloride; In acetone; at 100 ℃; for 72h;
DOI:10.1021/np0499665

Reference yield:

: 124689-65-2
cryptophycin-1

: 168569-15-1
cryptophycin-27

: 171674-92-3
cryptophycin-31

Guidance literature:: cryptophycin-1; With hydrogenchloride; In 1,2-dimethoxyethane; at 20 ℃; for 18h;

With potassium carbonate; In 1,2-dimethoxyethane; for 2h;
DOI:10.1021/np0499665

Reference yield:

: 124689-64-1
cryptophycin C

: 168569-15-1
cryptophycin-27

Guidance literature:: Multi-step reaction with 2 steps

1.1: 1.2 mg / m-chloroperbenzoic acid / CH₂Cl₂ / 2 h / 60 °C

2.1: aq. HCl / 1,2-dimethoxy-ethane / 18 h / 20 °C

2.2: 16 mg / K₂CO₃ / 1,2-dimethoxy-ethane / 2 h

With hydrogenchloride; 3-chloro-benzenecarboperoxoic acid; In 1,2-dimethoxyethane; dichloromethane;
DOI:10.1021/np0499665