Cryptophycin

Base Information Edit

Chemical Name:Cryptophycin
CAS No.:124689-65-2
Molecular Formula:C35H43 Cl N2 O8
Molecular Weight:655.188
Hs Code.:
UNII:XO974V2M5T
DSSTox Substance ID:DTXSID901046187
Wikidata:Q27293933
NCI Thesaurus Code:C1546
ChEMBL ID:CHEMBL441018
Mol file:124689-65-2.mol

Synonyms:cryptophycin;cryptophycin 1

Suppliers and Price of Cryptophycin

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
CRYPTOPHYCIN 95.00%
5MG
$ 503.75

Total 1 raw suppliers

Chemical Property of Cryptophycin Edit

Chemical Property:

Vapor Pressure:2.92E-32mmHg at 25°C
Boiling Point:889.4°C at 760 mmHg
Flash Point:491.7°C
PSA：139.54000
Density:1.171g/cm³
LogP:5.28580
XLogP3:6.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:8
Exact Mass:654.2707940
Heavy Atom Count:46
Complexity:1080

Purity/Quality:

≥ 98% ^*data from raw suppliers

CRYPTOPHYCIN 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1CNC(=O)C(NC(=O)C=CCC(OC(=O)C(OC1=O)CC(C)C)C(C)C2C(O2)C3=CC=CC=C3)CC4=CC(=C(C=C4)OC)Cl
Isomeric SMILES:C[C@@H]1CNC(=O)[C@H](NC(=O)/C=C/C[C@H](OC(=O)[C@@H](OC1=O)CC(C)C)[C@H](C)[C@@H]2[C@H](O2)C3=CC=CC=C3)CC4=CC(=C(C=C4)OC)Cl

Technology Process of Cryptophycin

There total 70 articles about Cryptophycin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 186665-99-6
(E)-(3S,6R,10R,16S)-16-((1R,2R,3R)-3-Chloro-2-hydroxy-1-methyl-3-phenyl-propyl)-10-(3-chloro-4-methoxy-benzyl)-3-isobutyl-6-methyl-1,4-dioxa-8,11-diaza-cyclohexadec-13-ene-2,5,9,12-tetraone

: 124689-65-2
cryptophycin-1

Guidance literature:: With potassium carbonate; In acetone;
DOI:10.1021/jo971645t

Reference yield: 72.0%

: 196794-26-0
(E)-(3S,6R,10R,16S)-10-(3-Chloro-4-methoxy-benzyl)-16-((1R,2R,3R)-2,3-dihydroxy-1-methyl-3-phenyl-propyl)-3-isobutyl-6-methyl-1,4-dioxa-8,11-diaza-cyclohexadec-13-ene-2,5,9,12-tetraone

: 124689-65-2
cryptophycin-1

Guidance literature:: (E)-(3S,6R,10R,16S)-10-(3-Chloro-4-methoxy-benzyl)-16-((1R,2R,3R)-2,3-dihydroxy-1-methyl-3-phenyl-propyl)-3-isobutyl-6-methyl-1,4-dioxa-8,11-diaza-cyclohexadec-13-ene-2,5,9,12-tetraone; With pyridinium p-toluenesulfonate; trimethyl orthoformate; In dichloromethane; at 20 ℃; for 2h;

With Acetyl bromide; In dichloromethane; at 20 ℃; for 4h;

With tetrabutylammomium bromide; potassium hydrogencarbonate; In 1,2-dimethoxyethane; at 40 ℃; for 27h;
DOI:10.1002/chem.200500282