7,12-Dioxaspiro[5.6]dodecane

Base Information

• Chemical Name: 7,12-Dioxaspiro[5.6]dodecane
• CAS No.: 181-28-2
• Deprecated CAS: 1315216-64-8
• Molecular Formula: C10H18O2
• Molecular Weight: 170.252
• Hs Code.: 2932999099
• European Community (EC) Number: 205-871-2
• UNII: 4W4M33FXV3
• DSSTox Substance ID: DTXSID5059747
• Nikkaji Number: J193.666B
• Wikidata: Q81988946
• Mol file: 181-28-2.mol

Synonyms:7,12-Dioxaspiro[5.6]dodecane;181-28-2;EINECS 205-871-2;7,12-Dioxaspiro(5.6)dodecane;4W4M33FXV3;SCHEMBL8909769;DTXSID5059747

Chemical Property of 7,12-Dioxaspiro[5.6]dodecane

Chemical Property:

• Vapor Pressure: 0.0929mmHg at 25°C
• Refractive Index: 1.475
• Boiling Point: 231.8°Cat760mmHg
• Flash Point: 87.8°C
• PSA: 18.46000
• Density: 1g/cm³
• LogP: 2.47380
• XLogP3: 2.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 170.130679813
• Heavy Atom Count: 12
• Complexity: 129

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CCC2(CC1)OCCCCO2

Technology Process of 7,12-Dioxaspiro[5.6]dodecane

There total 8 articles about 7,12-Dioxaspiro[5.6]dodecane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.7%

Butane-1,4-diol (110-63-4) + cyclohexanone (108-94-1,11119-77-0,9003-41-2,9075-99-4) → 7,12-dioxaspiro<5.6>dodecane (181-28-2)

Guidance literature:

With sulfonic group functionalized polyacrylonitrile preoxidated nanofiber mat; In cyclohexane; at 150 ℃; for 2h; Dean-Stark;

DOI:10.1016/j.apcata.2012.07.034

Reference yield:

Butane-1,4-diol (110-63-4) + 1-ethoxycyclohexene (1122-84-5) → 7,12-dioxaspiro<5.6>dodecane (181-28-2)

Guidance literature:

With toluene-4-sulfonic acid; Heating;

DOI:10.1016/0008-6215(85)85124-7

Reference yield:

4-<(cyclohex-1-enyl)oxy>butan-1-ol (175907-98-9) → 7,12-dioxaspiro<5.6>dodecane (181-28-2) + cyclohexanone (108-94-1,11119-77-0,9003-41-2,9075-99-4)

Guidance literature:

With acetic acid; In [D₃]acetonitrile; water;

DOI:10.1002/hlca.19960790106

upstream raw materials:

Butane-1,4-diol

cyclohexanone

1-ethoxycyclohexene

4-<(cyclohex-1-enyl)oxy>butan-1-ol

Downstream raw materials:

cyclohexanone

4-<(cyclohex-1-enyl)oxy>butan-1-ol

Hydroxy-butyl-cyclohexyl-ether

Refernces

• 1、 Du, Yijun,Shao, Linjun,Luo, Lingyan,Shi, Si,Qi, Chenze. "Preparation of a novel solid acid catalyst with Lewis and Bronsted acid sites and its application in acetalization". . p. 157 - 163. Retrieved 2014/02/14.
• 2、 Shao, Linjun,Xing, Guiying,He, Luyao,Chen, Ji,Xie, Hangqing,Liang, Xuezheng,Qi, Chenze. "Sulfonic groups functionalized preoxidated polyacrylonitrile nanofibers and its catalytic applications". . p. 133 - 137. Retrieved 2015/04/15.