N-methyl-N-nitrosooctanamide

Base Information

• Chemical Name: N-methyl-N-nitrosooctanamide
• CAS No.: 15567-46-1
• Molecular Formula: C₉H₁₈N₂O₂
• Molecular Weight: 186.254
• Mol file: 15567-46-1.mol

Synonyms:N-Methyl-N-nitrosooctanamide

Chemical Property of N-methyl-N-nitrosooctanamide

Chemical Property:

• Vapor Pressure: 0.0324mmHg at 25°C
• Boiling Point: 243.3°C at 760 mmHg
• Flash Point: 100.9°C
• Density: 1g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-methyl-N-nitrosooctanamide

There total 4 articles about N-methyl-N-nitrosooctanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

N-methyloctanoylamide (1119-57-9) → N-methyl-N-nitrosooctanoylamide (15567-46-1)

Guidance literature:

With polymer supported calixarene nitrosonium; In dichloromethane; at 20 ℃;

DOI:10.1016/j.tet.2004.08.063

Reference yield:

n-octanoic acid chloride (111-64-8) → N-methyl-N-nitrosooctanoylamide (15567-46-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 66 percent / aq. K₂CO₃ / ethyl acetate

2: calixarene-nitrosonium complex / CHCl₃ / 20 °C

With calixarene-nitrosonium; potassium carbonate; In chloroform; ethyl acetate;

DOI:10.1021/ja0392869

Reference yield:

n-octanoic acid chloride (111-64-8) → N-methyl-N-nitrosooctanoylamide (15567-46-1)

Guidance literature:

Multi-step reaction with 2 steps

1: aq. K₂CO₃ / ethyl acetate

2: 63 percent Spectr_. / calixarene-nitrosonium complex / CH₂Cl₂ / 20 °C

With calixarene-nitrosonium; potassium carbonate; In dichloromethane; ethyl acetate;

DOI:10.1002/chem.200400939

upstream raw materials:

N-methyloctanoylamide

n-octanoic acid chloride

Downstream raw materials:

N-benzyloctanoic amide

1-(pyrrolidin-1-yl)octan-1-one