2'-O-Acetylerythromycin A

Base Information Edit

Chemical Name:2'-O-Acetylerythromycin A
CAS No.:992-69-8
Molecular Formula:C₃₉H₆₉NO₁₄
Molecular Weight:775.975
Hs Code.:
UNII:S3Q5941GCW
Nikkaji Number:J451.187E
Wikidata:Q27893913
ChEMBL ID:CHEMBL2110577
Mol file:992-69-8.mol

Synonyms:2'-acetyl erythromycin stearate salt;erythromycin 2'-acetate;erythromycin acistrate

Suppliers and Price of 2'-O-Acetylerythromycin A

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
ERYTHROMYCIN 2'-ACETATE 95.00%
5MG
$ 499.60

Total 0 raw suppliers

Chemical Property of 2'-O-Acetylerythromycin A Edit

Chemical Property:

Vapor Pressure:3.74E-31mmHg at 25°C
Boiling Point:819.9°Cat760mmHg
Flash Point:449.7°C
PSA：199.98000
Density:1.2g/cm³
LogP:2.35640
XLogP3:3.3
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:15
Rotatable Bond Count:9
Exact Mass:775.47180587
Heavy Atom Count:54
Complexity:1290

Purity/Quality:: ERYTHROMYCIN 2'-ACETATE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC1C(C(C(C(=O)C(CC(C(C(C(C(C(=O)O1)C)OC2CC(C(C(O2)C)O)(C)OC)C)OC3C(C(CC(O3)C)N(C)C)OC(=O)C)(C)O)C)C)O)(C)O
Isomeric SMILES:CC[C@@H]1[C@@]([C@@H]([C@H](C(=O)[C@@H](C[C@@]([C@@H]([C@H]([C@@H]([C@H](C(=O)O1)C)O[C@H]2C[C@@]([C@H]([C@@H](O2)C)O)(C)OC)C)O[C@H]3[C@@H]([C@H](C[C@H](O3)C)N(C)C)OC(=O)C)(C)O)C)C)O)(C)O

Technology Process of 2'-O-Acetylerythromycin A

There total 4 articles about 2'-O-Acetylerythromycin A which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 108-24-7
acetic anhydride

: 114-07-8
erythromycin

: 992-69-8,86784-08-9
2'-O-acetylerythromycin A

Guidance literature:: With pyridine; In ethyl acetate; at 20 ℃; for 1h;
DOI:10.1002/ardp.200900288

Reference yield: 70.0%

: 108-24-7
acetic anhydride

: 114-07-8
erythromycin

: C₄₁H₇₁NO₁₅

: 992-69-8,86784-08-9
2'-O-acetylerythromycin A

Guidance literature:: With pyridine; at 25 ℃; for 72h;
DOI:10.1002/anie.200601490

Reference yield:

: 108-24-7
acetic anhydride

: 114-07-8
erythromycin

: C₄₁H₇₁NO₁₅

: C₄₃H₇₃NO₁₆

: C₄₁H₇₁NO₁₅

: 992-69-8,86784-08-9
2'-O-acetylerythromycin A

Guidance literature:: With triethylamine; In dichloromethane; chloroform; at 25 ℃; for 24h; Title compound not separated from byproducts.;
DOI:10.1002/anie.200601490