Pyrrole, 1,3,4-trimethyl-

Base Information

• Chemical Name: Pyrrole, 1,3,4-trimethyl-
• CAS No.: 30144-12-8
• Molecular Formula: C₇H₁₁N
• Molecular Weight: 109.171
• DSSTox Substance ID: DTXSID30184226
• Nikkaji Number: J379.557H
• Wikidata: Q83055113
• Mol file: 30144-12-8.mol

Synonyms:Pyrrole, 1,3,4-trimethyl-;30144-12-8;Pyrrole,1,3,4-trimethyl-;SCHEMBL348022;DTXSID30184226

Chemical Property of Pyrrole, 1,3,4-trimethyl-

Chemical Property:

• Vapor Pressure: 2.56mmHg at 25°C
• Boiling Point: 164.6°Cat760mmHg
• Flash Point: 53.4°C
• Density: 0.87g/cm³
• XLogP3: 1.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 0
• Exact Mass: 109.089149355
• Heavy Atom Count: 8
• Complexity: 70.5

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CN(C=C1C)C

Technology Process of Pyrrole, 1,3,4-trimethyl-

There total 9 articles about Pyrrole, 1,3,4-trimethyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 1,3,4-trimethyl-pyrrole (30144-12-8)

Guidance literature:

With water; silver(l) oxide; unter Stickstoff, Eindampfen der Reaktionsloesung und Erhitzen des Rueckstands unter 0,1 Torr bis auf 130grad;

DOI:10.1021/ja01604a060

Reference yield:

thiophene-3,3,4,4-tetracarboxylic acid tetraethyl ester (101448-83-3) → 1,3,4-trimethyl-pyrrole (30144-12-8)

Guidance literature:

Multi-step reaction with 4 steps

1: aq. NaOH solution; dioxane / Erhitzen des nach dem Ansaeuern erhaltenen Reaktionsprodukts

2: concentrated H₂SO₄

3: LiAlH₄; diethyl ether

4: H₂O; Ag₂O / Erhitzen des Reaktionsprodukts

With 1,4-dioxane; sodium hydroxide; lithium aluminium tetrahydride; diethyl ether; sulfuric acid; water; silver(l) oxide;

DOI:10.1021/ja01604a060

Reference yield:

cis-3,4-dicarboxythiacyclopentane anhydride (16810-52-9) → 1,3,4-trimethyl-pyrrole (30144-12-8)

Guidance literature:

Multi-step reaction with 3 steps

1: concentrated H₂SO₄

2: LiAlH₄; diethyl ether

3: H₂O; Ag₂O / Erhitzen des Reaktionsprodukts

With lithium aluminium tetrahydride; diethyl ether; sulfuric acid; water; silver(l) oxide;

DOI:10.1021/ja01604a060

upstream raw materials:

5-methyl-(3ar,6ac)-hexahydro-thieno[3,4-c]pyrrole

3,4-dimethyl-1H-pyrrole

methyl iodide

methyl p-toluene sulfonate

Downstream raw materials:

1,3,4-trimethyl-1,5-dihydro-2H-pyrrol-2-one