N-(4-Hydroxyphenyl)stearamide

Base Information

• Chemical Name: N-(4-Hydroxyphenyl)stearamide
• CAS No.: 103-99-1
• Molecular Formula: C24H41NO2
• Molecular Weight: 375.595
• Hs Code.: 2924299090
• European Community (EC) Number: 203-165-9
• NSC Number: 166354
• DSSTox Substance ID: DTXSID6059287
• Nikkaji Number: J182.174A
• Wikidata: Q81988731
• Mol file: 103-99-1.mol

Synonyms:N-(4-Hydroxyphenyl)stearamide;103-99-1;N-Stearoyl-p-aminophenol;Octadecanamide, N-(4-hydroxyphenyl)-;N-(4-hydroxyphenyl)octadecanamide;Suconox-18;Stearoyl-p-aminophenol;p-(Steroylamino)phenol;N-Stearoyl-4-aminophenol;Stearic acid-p-hydroxyanilide;Suconox 18, 4'-hydroxy-;Octadecanamide,N-(4-hydroxyphenyl)-;N-4-Hydroxyphenylstearamide;NSC 166354;Octadecananilide, 4'-hydroxy-;EINECS 203-165-9;C24H41NO2;Suconox 18;4-hydroxystearanilide;Stearoyl p-aminophenol;N-stearoyl p-amino phenol;N-4-hydroxyphenylstearamid;Stearamide, m-hydroxyphenol;SCHEMBL39282;4'-HYDROXYSTEARANILIDE;BIDD:ER0270;DTXSID6059287;N-(4-Hydroxyphenyl) Stearamide;NSC166354;AKOS024319103;NSC-166354;J-001085

Chemical Property of N-(4-Hydroxyphenyl)stearamide

Chemical Property:

• Vapor Pressure: 2.25E-12mmHg at 25°C
• Melting Point: 131-133 °C(lit.)
• Refractive Index: 1.517
• Boiling Point: 542.3 °C at 760 mmHg
• PKA: 10.12±0.26(Predicted)
• Flash Point: 281.8 °C
• PSA: 49.33000
• Density: 0.975 g/cm³
• LogP: 7.66520
• XLogP3: 9.4
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 17
• Exact Mass: 375.313729551
• Heavy Atom Count: 27
• Complexity: 337

Purity/Quality:

98%,99%, ^*data from raw suppliers

4'-HYDROXYSTEARANILIDE Aldrich ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CCCCCCCCCCCCCCCCCC(=O)NC1=CC=C(C=C1)O
• Uses: Antioxidant.

Technology Process of N-(4-Hydroxyphenyl)stearamide

There total 5 articles about N-(4-Hydroxyphenyl)stearamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

4-amino-phenol (123-30-8) + stearic acid (57-11-4) → 4-Octadecanoylamino-phenol (103-99-1)

Guidance literature:

With 2-bromo-1-methyl-pyridinium iodide; triethylamine; In dichloromethane; at 60 ℃; for 0.5h;

DOI:10.1248/cpb.28.2941

Reference yield:

stearic acid (57-11-4) → 4-Octadecanoylamino-phenol (103-99-1)

Guidance literature:

Multi-step reaction with 2 steps

1: oxalyl chloride / CH₂Cl₂ / 0.5 h / Heating

2: butan-2-one / 1 h / 0 - 5 °C

With oxalyl dichloride; In dichloromethane; butanone;

DOI:10.1248/cpb.28.2941

Reference yield:

4-amino-phenol (123-30-8) + Stearoyl chloride (112-76-5) → 4-Octadecanoylamino-phenol (103-99-1)

Guidance literature:

In butanone; at 0 - 5 ℃; for 1h;

DOI:10.1248/cpb.28.2941

upstream raw materials:

4-amino-phenol

stearic acid

4-acetaminophenol

Stearoyl chloride

Refernces

• 1、 -. "2-Propanol derivatives as corrosion inhibitors". . . Retrieved 2008/06/13.
• 2、 -. "Triazole-organodithiophosphate reaction product additives for functional fluids". . . Retrieved 2008/06/13.