5-hydroxysulfadimidine

Base Information

• Chemical Name: 5-hydroxysulfadimidine
• CAS No.: 51395-19-8
• Molecular Formula: C12H14 N4 O3 S
• Molecular Weight: 294.334
• Mol file: 51395-19-8.mol

Synonyms:5-Hydroxy-4,6-dimethyl-2-(sulfanilamido)pyrimidine;5-Hydroxysulfadimidine

Chemical Property of 5-hydroxysulfadimidine

Chemical Property:

• Vapor Pressure: 9.33E-14mmHg at 25°C
• Boiling Point: 573.5°Cat760mmHg
• Flash Point: 300.7°C
• PSA: 126.58000
• Density: 1.484g/cm³
• LogP: 2.91700

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-hydroxysulfadimidine

There total 2 articles about 5-hydroxysulfadimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

sulfadimesine (57-68-1) → 2-Amino-4,6-dimethylpyrimidine (767-15-7,184433-59-8) + N-(4,6-dimethyl-2-pyrimidine)-1,4-phenylenediamine (81261-93-0) + N-(4,6-dimethyl-2-pyrimidine)-4-N-(benzenesulfonamide)benzenesulfonamide + N-(4,6-dimethyl-2-pyrimidine)-4-N-(4,6-dimethylpyrimidine)benzenesulfonamide + 2-amino-5-hydroxypyrimidine-4,6(1H,3H)-dione + 5-Hydroxysulphadimidine (51395-19-8) + 4-aminobenzene sulfonic acid (121-57-3,856062-06-1)

Guidance literature:

With ferrous(II) sulfate heptahydrate; zinc(II) sulfate heptahydrate; potassium dihydrogenphosphate; magnesium sulfate heptahydrate; copper(II) choride dihydrate; calcium(II) chloride dihydrate; manganese(II) chloride tetrahydrate; cobalt(II) chloride hexahydrate; sodium molybdate dihydrate; sodium acetate; boric acid; ammonium chloride; potassium iodide; corn starch; In water; at 20 ℃; Microbiological reaction;

DOI:10.1016/j.cclet.2019.08.031

Reference yield:

sulfadimesine (57-68-1) → 2-Amino-4,6-dimethylpyrimidine (767-15-7,184433-59-8) + 2-amino-4,6-dimethyl-5-pyrimidinol (685897-68-1) + 4-amino-benzenesulphone + carbon dioxide (124-38-9,18923-20-1) + C12H14N4O4S + C12H14N4O3S + 4-amino-phenol (123-30-8) + 5-Hydroxysulphadimidine (51395-19-8) + 4-aminobenzene sulfonic acid (121-57-3,856062-06-1)

Guidance literature:

With titanium(IV) oxide; for 1h; pH=5.5; pH-value; Kinetics; Darkness;

DOI:10.1039/c6ra13435a

upstream raw materials:

sulfadimesine

Refernces

• 1、 Tzeng, Tai-Wei,Wang, Shan-Li,Chen, Chiing-Chang,Tan, Chen-Chung,Liu, Yu-Ting,Chen, Tsan-Yao,Tzou, Yu-Min,Chen,Hung. "Photolysis and photocatalytic decomposition of sulfamethazine antibiotics in an aqueous solution with TiO2". . p. 69301 - 69310. Retrieved 2016/08/05.