5H-Pyrido(4,3-b)indole, 3-amino-4-ethyl-1-methyl-, acetate

Base Information

Chemical Name:5H-Pyrido(4,3-b)indole, 3-amino-4-ethyl-1-methyl-, acetate
CAS No.:75240-22-1
Molecular Formula:C14H15N3•C2H4O2
Molecular Weight:285.38
Hs Code.:2933990090
DSSTox Substance ID:DTXSID80226226
Mol file:75240-22-1.mol

Synonyms:75240-22-1;3-Amino-4-ethyl-1-methyl-5H-pyrido(4,3-b)indole acetate;5H-Pyrido(4,3-b)indole, 3-amino-4-ethyl-1-methyl-, acetate;4-Ethyl-1-methyl-5H-pyrido(4,3-b)indol-3-amine monoacetate;5H-Pyrido(4,3-b)indol-3-amine, 4-ethyl-1-methyl-, monoacetate;DTXSID80226226;LS-133405

Suppliers and Price of 5H-Pyrido(4,3-b)indole, 3-amino-4-ethyl-1-methyl-, acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 5H-Pyrido(4,3-b)indole, 3-amino-4-ethyl-1-methyl-, acetate

Chemical Property:

Vapor Pressure:8.05E-09mmHg at 25°C
Boiling Point:464.9°C at 760 mmHg
Flash Point:266°C
PSA：92.73000
LogP:3.19010
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:285.147726857
Heavy Atom Count:21
Complexity:312

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC1=C2C(=C(N=C1N)C)C3=CC=CC=C3N2.CC(=O)O

Technology Process of 5H-Pyrido(4,3-b)indole, 3-amino-4-ethyl-1-methyl-, acetate

There total 4 articles about 5H-Pyrido(4,3-b)indole, 3-amino-4-ethyl-1-methyl-, acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 12.0%

: 64-19-7,77671-22-8
acetic acid

: 78788-93-9
2-(1-cyanopropyl)indole

: 75-05-8,26809-02-9
acetonitrile

: 75240-22-1
4-Ethyl-1-methyl-5H-pyrido[4,3-b]indol-3-ylamine; compound with acetic acid

Guidance literature:: aluminium trichloride; at 100 - 120 ℃; for 12h;
DOI:10.1248/cpb.29.1280

Reference yield:

: 52618-53-8
2-(cyanomethyl)-N-ethoxycarbonylindole

: 75240-22-1
4-Ethyl-1-methyl-5H-pyrido[4,3-b]indol-3-ylamine; compound with acetic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 55 percent / LDA / tetrahydrofuran / -78 °C

2: 90 percent / K₂CO₃ / methanol / Ambient temperature

3: 12 percent / aluminum chloride / 12 h / 100 - 120 °C

With potassium carbonate; lithium diisopropyl amide; aluminium trichloride; In tetrahydrofuran; methanol;
DOI:10.1248/cpb.29.1280

Reference yield:

: 17954-23-3
1-ethoxycarbonyl-1,2-dihydroquinoline-2-carbonitrile

: 75240-22-1
4-Ethyl-1-methyl-5H-pyrido[4,3-b]indol-3-ylamine; compound with acetic acid

Guidance literature:: Multi-step reaction with 4 steps

1: Irradiation

2: 55 percent / LDA / tetrahydrofuran / -78 °C

3: 90 percent / K₂CO₃ / methanol / Ambient temperature

4: 12 percent / aluminum chloride / 12 h / 100 - 120 °C

With potassium carbonate; lithium diisopropyl amide; aluminium trichloride; In tetrahydrofuran; methanol;
DOI:10.1248/cpb.29.1280