1-(2,4-dichlorobenzyl)-2-methyl-1H-indole-3-carbaldehyde

Base Information

Chemical Name:1-(2,4-dichlorobenzyl)-2-methyl-1H-indole-3-carbaldehyde
CAS No.:92407-87-9
Molecular Formula:C17H13Cl2NO
Molecular Weight:318.202
Hs Code.:2933990090
DSSTox Substance ID:DTXSID101165381
Mol file:92407-87-9.mol

Synonyms:1-(2,4-dichlorobenzyl)-2-methyl-1H-indole-3-carbaldehyde;92407-87-9;ASISCHEM R25223;1-[(2,4-dichlorophenyl)methyl]-2-methylindole-3-carbaldehyde;SCHEMBL6706679;DTXSID101165381;STK698102;AKOS000289126;CS-0363335;1-[(2,4-Dichlorophenyl)methyl]-2-methyl-1H-indole-3-carboxaldehyde

Suppliers and Price of 1-(2,4-dichlorobenzyl)-2-methyl-1H-indole-3-carbaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 1-(2,4-dichlorobenzyl)-2-methyl-1H-indole-3-carbaldehyde

Chemical Property:

PSA：22.00000
LogP:5.11730
XLogP3:4.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:3
Exact Mass:317.0374194
Heavy Atom Count:21
Complexity:378

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C2=CC=CC=C2N1CC3=C(C=C(C=C3)Cl)Cl)C=O

Technology Process of 1-(2,4-dichlorobenzyl)-2-methyl-1H-indole-3-carbaldehyde

There total 2 articles about 1-(2,4-dichlorobenzyl)-2-methyl-1H-indole-3-carbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 5416-80-8
2-methyl-1H-indole-3-carbaldehyde

: 94-99-5
2,4-Dichlorobenzyl chloride

: 92407-87-9
1-(2,4-dichlorobenzyl)-3-formyl-2-methyl-1H-indole

Guidance literature:: With sodium hydride; In dimethyl sulfoxide; at 20 ℃; for 2h;
DOI:10.1016/S0223-5234(02)00005-3

Reference yield:

: 95-20-5
2-methyl-1H-indole

: 92407-87-9
1-(2,4-dichlorobenzyl)-3-formyl-2-methyl-1H-indole

Guidance literature:: Multi-step reaction with 2 steps

1.1: phosphorus oxychloride / 2 h / 5 - 20 °C

1.2: 90 percent / potassium hydroxide / H₂O

2.1: 80 percent / NaH / dimethylsulfoxide / 2 h / 20 °C

With sodium hydride; trichlorophosphate; In dimethyl sulfoxide; 1.1: Vilsmeier-Haack reaction;
DOI:10.1016/S0223-5234(02)00005-3