1-[(2,4-DICHLOROPHENYL)METHYL]-2-METHYL-1H-INDOLE-3-METHANOL

Base Information

Chemical Name:1-[(2,4-DICHLOROPHENYL)METHYL]-2-METHYL-1H-INDOLE-3-METHANOL
CAS No.:92408-02-1
Molecular Formula:C17H15Cl2NO
Molecular Weight:320.218
Hs Code.:
Mol file:92408-02-1.mol

Synonyms:[1-(2,4-Dichloro-benzyl)-2-methyl-1H-indol-3-yl]-methanol;

Suppliers and Price of 1-[(2,4-DICHLOROPHENYL)METHYL]-2-METHYL-1H-INDOLE-3-METHANOL

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
1-[(2,4-DICHLOROPHENYL)METHYL]-2-METHYL-1H-INDOLE-3-METHANOL 95.00%
5MG
$ 502.30

Total 3 raw suppliers

Chemical Property of 1-[(2,4-DICHLOROPHENYL)METHYL]-2-METHYL-1H-INDOLE-3-METHANOL

Chemical Property:

PSA：25.16000
LogP:4.79710

Purity/Quality:: 1-[(2,4-DICHLOROPHENYL)METHYL]-2-METHYL-1H-INDOLE-3-METHANOL 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1-[(2,4-DICHLOROPHENYL)METHYL]-2-METHYL-1H-INDOLE-3-METHANOL

There total 4 articles about 1-[(2,4-DICHLOROPHENYL)METHYL]-2-METHYL-1H-INDOLE-3-METHANOL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 92407-87-9
1-(2,4-dichlorobenzyl)-3-formyl-2-methyl-1H-indole

: 92408-02-1
1-(2,4-dichlorobenzyl)-3-hydroxymethyl-2-methyl-1H-indole

Guidance literature:: With sodium tetrahydroborate; In isopropyl alcohol; Ambient temperature;
DOI:10.1002/ardp.19843170803

Reference yield:

: 5416-80-8
2-methyl-1H-indole-3-carbaldehyde

: 92408-02-1
1-(2,4-dichlorobenzyl)-3-hydroxymethyl-2-methyl-1H-indole

Guidance literature:: Multi-step reaction with 2 steps

1: 80 percent / NaH / dimethylsulfoxide / 2 h / 20 °C

2: 96 percent / LiAlH₄ / tetrahydrofuran / 0.5 h / 20 °C

With lithium aluminium tetrahydride; sodium hydride; In tetrahydrofuran; dimethyl sulfoxide;
DOI:10.1016/S0223-5234(02)00005-3

Reference yield:

: 95-20-5
2-methyl-1H-indole

: 92408-02-1
1-(2,4-dichlorobenzyl)-3-hydroxymethyl-2-methyl-1H-indole

Guidance literature:: Multi-step reaction with 3 steps

1.1: phosphorus oxychloride / 2 h / 5 - 20 °C

1.2: 90 percent / potassium hydroxide / H₂O

2.1: 80 percent / NaH / dimethylsulfoxide / 2 h / 20 °C

3.1: 96 percent / LiAlH₄ / tetrahydrofuran / 0.5 h / 20 °C

With lithium aluminium tetrahydride; sodium hydride; trichlorophosphate; In tetrahydrofuran; dimethyl sulfoxide; 1.1: Vilsmeier-Haack reaction;
DOI:10.1016/S0223-5234(02)00005-3